Machine learning to predict the clinical utility of biomedical research

A machine learning model to predict which scientific advances are likely to eventually translate to the clinic has been developed by Ian Hutchins and colleagues in the Office of Portfolio Analysis (OPA), a team led by George Santangelo at the National Institutes of Health (NIH). This work published in the journal PLOS Biology aims to … Continue reading Machine learning to predict the clinical utility of biomedical research

New microfluidic system using artificial membrane keep brain tissue viable for a longer duration

Researchers at the RIKEN Center for Biosystems Dynamics Research in Japan have developed a new system for keeping tissue viable for long-term study once transferred from an animal to a culture medium. The new system uses a microfluidic device made of polydimethylsiloxane (PDMS) with a porous membrane that can keep tissue from both drying out … Continue reading New microfluidic system using artificial membrane keep brain tissue viable for a longer duration

Researchers develop self sterilizing bacterial air filter using graphene

Rice University researchers have developed self-sterilizing bacterial air filters using graphene. Workings of this novel air filter are published in the American Chemical Society journal ACS Nano. This devise captures bacteria, fungi, spores, prions, endotoxins and other biological contaminants carried by droplets, aerosols and particulate matter. The filter then prevents the microbes and other contaminants … Continue reading Researchers develop self sterilizing bacterial air filter using graphene

In Russia, lower alcohol consumption associated with increase in life expectancy

A study published in the Journal of Studies on Alcohol & Drugs shown that there is a correlation between lower alcohol consumption and decreased mortality rate. According to the research life expectancy for men and women is 6.1 and 4.7 years longer than it was in 1980, with alcohol consumption patterns playing a significant role. … Continue reading In Russia, lower alcohol consumption associated with increase in life expectancy

Increased mortality associated with short sleep duration

According to a new study published in the Journal of the American Heart Association middle-aged adults with high blood pressure, type 2 diabetes, heart disease or stroke could be at high risk for cancer and early death when sleeping less than six hours per day. This study was done on a total of 1654 adults … Continue reading Increased mortality associated with short sleep duration

Researchers identify role of protein TOM-1 in Alzheimer’s disease pathology

The scientists from the University of California Irvine discovered that reducing the amount of protein TOM-1 in Alzheimer's rodent models increased pathology, which included increased inflammation, and exacerbated cognitive problems associated with the disease and restoring TOM-1 levels reversed those effects. This research is significant as it explores the molecular pathways underlying Alzheimer's disease. It … Continue reading Researchers identify role of protein TOM-1 in Alzheimer’s disease pathology

Optoceutics: controlling regenerative cells using visual light.

For the first time, the research group from Istituto Italiano di Tecnologia (IIT) in Milan proposed an innovative strategy to gain optical control of epithelial regenerative cells by using visible light together with photo-sensitive and bio-compatible conjugated polymers used as photo-actuators. This research is published in Science Advances. In this study, the researchers managed to … Continue reading Optoceutics: controlling regenerative cells using visual light.

New technology to monitor chemotherapy using magnetic nanoparticles

Researchers from Michigan State University propose a novel non-invasive magnetic particle imaging (MPI) to monitor chemotherapy release in vivo. This method employs superparamagnetic nanoparticles as the contrast agent to monitor drug release in the body. In this study researchers designed iron oxide nanocomposite loaded with a chemotherapy drug doxorubicin which serves as a drug delivery … Continue reading New technology to monitor chemotherapy using magnetic nanoparticles

Machine learning algorithms to speed up image biomarker analysis in heart MRI scans

According to research published in journal Circulation:Cardiaovascular imaging cardiac MRI analysis utilizing machine learning algorithms can be performed significantly faster and with similar precision compared to human experts. In the study, researchers trained a neural network to read the cardiac MRI scans. Utilizing artificial intelligence, a scan can be analyzed in approximately four seconds compared … Continue reading Machine learning algorithms to speed up image biomarker analysis in heart MRI scans

Fat mass index better predictor of cardiovascular events in diabetics

According to research published in the Canadian Medical Association Journal, type 2 diabetics with higher fat mass index are prone to develop cardiovascular events. The study showed that fat mass index (FMI) is superior to lean body mass index (BMI) in predicting heart-related events. Researchers conducted a post hoc analysis of data from the Action … Continue reading Fat mass index better predictor of cardiovascular events in diabetics