Category: Neurology
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Machine Learning Model To Predict Dementia Mortality
Researchers at the Icahn School of Medicine at Mount Sinai have employed machine learning, specifically the XGBoost algorithm, to accurately predict mortality in dementia patients, marking a significant shift toward prognosis in dementia research. By analyzing data from over 45,000 participants, the study identifies predictors for survival, demonstrating high predictive accuracy and the potential for…
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Advanced Predictive Model for Alzheimer’s Using Electronic Health Records and Knowledge Networks
Researchers have leveraged electronic health records from UCSF and SPOKE knowledge networks to predict Alzheimer’s Disease onset and understand its biological basis, including gender-specific impacts. The study achieved high predictive accuracy by analyzing conditions co-occurring with Alzheimer’s across millions of patient records, using random forest models for analysis.
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iTalkBetter App: Aphasia Rehabilitation Through Digital Speech Therapy
iTalkBetter, an innovative medical app created by the Neurotherapeutics Group at University College London, offers a breakthrough digital speech therapy for aphasia patients, enhancing traditional therapy limits with over 200 practice words and real-time feedback mechanisms. Clinical trials have shown a significant improvement in users’ naming ability, with lasting effects and increased brain activity in…
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Novel Biomimetic Neurostimulation Framework To Improve Neuroprosthetics
Researchers at ETH Zurich’s Neuroengineering Lab have developed a groundbreaking prosthetic leg that connects to the sciatic nerve, enabling amputees to feel natural sensations from their artificial limbs. This innovative approach, utilizing a biomimetic neurostimulation framework developed with computational model named FootSim and animal studies to mimics natural neural activities, significantly enhancing mobility and overall…
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Novel Memory Decoding Model And Neural Prosthetics To Enhance Memory
Researchers from Wake Forest University School of Medicine and the University of Southern California (USC) successfully enhanced memory using a memory decoding model based on individual brain patterns, improving memory recall in epileptic patients. This breakthrough paves the way for neural prosthetics to treat memory loss in conditions like Alzheimer’s and stroke.
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Low-Intensity Focused Ultrasound Deep Brain Modulation For Pain Management
Researchers at the Fralin Biomedical Research Institute have demonstrated that low-intensity focused ultrasound (LIFU) can non-invasively modulate the activity of the insula in the brain, reducing pain perception. This groundbreaking study highlights the potential of LIFU as a novel, site-specific approach to pain management.
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Study Links Mitochondrial Dysfunction to Alzheimer’s Synapse Loss
Researchers at Scripps Institute have linked dysfunctional mitochondrial metabolism to synaptic loss in Alzheimer’s, discovering that energy production impairment in brain cell mitochondria leads to cognitive decline. The study, using human neuron models, identifies a block in the TCA cycle crucial for energy production and demonstrates that restoring the cycle can reverse synapse loss, offering…
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DETree: A Learning-Based Framework for Alzheimer’s Progression Prediction
Researchers at The University of Texas at Arlington have developed DETree, a groundbreaking learning-based framework for predicting the progression of Alzheimer’s disease. Utilizing data from 266 individuals, DETree surpasses traditional models, offering potential applications in other multi-stage diseases.
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Handwriting could foster better memory
A Norwegian University of Science and Technology study found that handwriting activates more complex brain connectivity patterns than typing, especially in regions crucial for memory and learning. The study, involving 36 students and a 256-channel EEG sensor array, suggests handwriting’s significant role in learning and brain development, highlighting its importance in educational practices.
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Soft Robotic Apparel Aids Parkinson’s Patients with Freezing of Gait
Innovative research by a team from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) and Boston University Sargent College of Health & Rehabilitation Sciences developed a soft, wearable robotic apparel worn around the hips and thighs that assists with leg movement to address freezing of gait (FoG), a significant impediment in…
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