Machine learning algorithm to predict mortality in heart failure patients

Researchers from the University of California San Diego developed a machine-learning model by training a boosted decision tree algorithm on de-identified electronic health records data of 5,822 hospitalized or ambulatory patients with heart failure from the University of California San Diego. This machine learning model is based on eight readily available variables. These include, diastolic … Continue reading Machine learning algorithm to predict mortality in heart failure patients

Calculator to predict five year risk for chronic kidney disease

A new risk calculator tool to predict the risk of chronic kidney disease is developed by Chronic Kidney Disease Prognosis Consortium, a large global collaboration led by researchers at the Johns Hopkins Bloomberg School of Public Health. It utilizes a mix of variables to predict accurately whether someone is likely to develop chronic kidney disease … Continue reading Calculator to predict five year risk for chronic kidney disease

Increased mortality associated with short sleep duration

According to a new study published in the Journal of the American Heart Association middle-aged adults with high blood pressure, type 2 diabetes, heart disease or stroke could be at high risk for cancer and early death when sleeping less than six hours per day. This study was done on a total of 1654 adults … Continue reading Increased mortality associated with short sleep duration

Animal tests show promise for needle free flu vaccine patch

Researchers from the University of Rochester Medical Center published a study in the Journal of Investigative Dermatology about a technology that could replace needle-based vaccination methods. In this study, researchers utilized a synthetic peptide to bind and inhibit the claudin-1 protein. Claudin-1 protein is essential for skin barrier strength and decreases the permeability of the … Continue reading Animal tests show promise for needle free flu vaccine patch

New retinal biomarker for identifying early Alzheimer’s disease

Researchers at the Complutense University of Madrid (UCM) have identified changes in retinal layer thickness, inflammation or thinning in patients with mild Alzheimer's disease. These changes are identified with non invasive assessment using optical coherence tomography may be an important biomarker for early diagnosis. Researchers observed that in some patients diagnosed with Alzheimer's disease, the … Continue reading New retinal biomarker for identifying early Alzheimer’s disease

Use of mobile phone games to assess cognitive decline

Researchers from University of Kent shown that mobile phone games could be used as new tool for identifying early signs of cognitive decline and thus identify a possibility of developing dementia. Investigating the link between patterns of tap, swipe and rotational gestures during mobile game play and the users' cognitive performance, the research shows that … Continue reading Use of mobile phone games to assess cognitive decline

Macrophage protein shown to have major role in fracture healing

Duke Health researchers previously showed that introducing bone marrow stem cells to a bone injury can expedite healing, but the exact process was unclear. Now researchers found that macrophage and the proteins it secretes called low-density lipoprotein receptor-related protein 1 (Lrp1) can have a rejuvenating effect on tissue. These findings are published in journal Nature Communications.After tissue … Continue reading Macrophage protein shown to have major role in fracture healing

Scientists identify neural pathways behind visual perceptual decision-making

Scientists at the National Eye Institute (NEI) have found that neurons in the superior colliculus are key players in allowing us to detect visual objects and events. This structure doesn't help us recognize what the specific object or event is; instead, it's the part of the brain that decides something is there at all. In this … Continue reading Scientists identify neural pathways behind visual perceptual decision-making

Early diagnosis of Alzheimer’s disease using artificial intelligence

According to a study published in the journal of radiology, research shows that artificial intelligence (AI) technology predict the development of Alzheimer's disease early.Early diagnosis of Alzheimer's is important as treatments and interventions are more effective early in the course of the disease. However, early diagnosis has proven to be challenging. Research has linked the disease … Continue reading Early diagnosis of Alzheimer’s disease using artificial intelligence

Keep up with your weight loss goals with daily weighing

According to research presented in the American Heart Association's 2018 scientific meeting, daily weighing may help with weight loss goals. People who don't weigh themselves at all or rarely were less likely to lose weight than those who weighed themselves often,Researchers examined the self-weighing patterns of 1,042 adults (78 percent male, 90 percent white, average age … Continue reading Keep up with your weight loss goals with daily weighing