Category: Uncategorized
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New body-on-a-chip technology to advance pharmacological research
Researchers from MIT have developed “physiome on chip” technology that could be used to evaluate new drugs and detect side effects before the drugs are tested in human clinical trials. This could be used an alternative to animal testing for pharmacological testing before human clinical trials. Body on a chip. Credit: Felice Frankel They used…
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New asthma management (APGAR) tools improve outcomes
Researchers analyzed to see if a set of asthma management tools called APGAR(Activities, Persistent, triGGers, Asthma medications, Response to therapy) tools helps decrease asthma-related visits to the emergency department, urgent care or hospital and improves patients’ asthma control. The study results are published in journal Annals of Family Medicine. A randomized controlled study was conducted in 18…
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A new approach to create targeted nanovesicles for cancer treatment
Researchers have used autologous immune cells from the mouse to create nanovesicles to be used in the delivery of drugs to tumors. This technique helped them to create a sufficient number of nanovesicles inexpensively to be used as drug delivery system. This image shows ligands-grafted extracellular vesicles as drug delivery vehicles.Credit: Xin Zou Cells naturally…
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New nanosensor technology to detect osteoarthritis biomarker
Researchers at Wake Forest Baptist Medical Center have been able to analyze hyaluronic acid using solid-state nanopore sensor. This technique allows them to study its role in osteoarthritis and other inflammatory joint disorders. This technique is first of a kind and is a significant improvement regarding relative ease to perform and high precision from other…
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Understanding molecular mechanisms behind germinal matrix hemorrhage
Researchers have utilized a mouse model to determine the molecular mechanisms underlying germinal matrix hemorrhage. Nearly 12,000 premature infants born annually in the US are affected by neonatal brain hemorrhage which results in mortality and long-term morbidity. Unfortunately, no treatment exists for this condition, and the only preventive measure is steroids before birth, which has…
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New biomarkers to predict the success of diabetic macular edema treatment
Researchers have found new biomarkers that predict prognosis following current treatments for diabetic macular edema. The research was led by Dr. Rajeev Muni, a vitreoretinal surgeon at St. Michael’s Hospital. The study is published in the journal JAMA Ophthalmology. Diabetic macular edema is one the common complication of Diabetes. It is associated with the accumulation of fluid in the…
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Cost of care for falls in elderly population
Researchers estimated medical costs attributable to both fatal and nonfatal falls in the elderly population and found that approximately 50 billion dollars were spent in 2015. These findings are published in the Journal of the American Geriatrics Society. Researchers utilized population data from the National Vital Statistics System (NVSS) and cost estimates from the Web-based Injury Statistics…
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New biomarkers for assessing Alzheimers dementia risk and early diagnosis
Researchers from the University of Texas have analyzed biomarkers to predict future risk of dementia. Their findings are published in journal Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. Dementia is a rising tidal wave of devastation for families and society. Age is the biggest risk factor. Alzheimer’s disease, which is the leading cause…
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Total joint replacement procedure projections 2030 to 2060
Total joint replacement (TJR) is one of the most commonly performed surgical procedure in the United States, and the volume of primary and revision total joint replacement procedures have increased consistently in past decade. New research presented at the 2018 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) analyzed models to predict the…
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A new algorithm to solve memory problems in large-scale human brain simulations
Researchers have come closer towards advancing technology to create computer simulations of the brain networks using exascale-class supercomputers. Their findings are published in journal Frontiers in Neuroinformatics. Credit: Forschungszentrum Jülich The human brain is a complex network composed of approximately 100 billion neurons. With current computing power, it is impossible to simulate 100 percent working brain.…
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