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University of Texas researchers developing radiotherapeutic gold nanoseeds to fight inoperable tumors

Many solid tumors are considered inoperable because they adhere to vital structures or the surgery would cause irreversible damages to the patients. In order to prevent the tumor growth or provide complete tumor resolution without surgery, chemotherapy and radiation are currently in clinical practice. Since these tumors are already locally advanced or have begun to …

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Research shows tumor-targeted radiosensitization using antibody drug conjugates may redues toxicity and improve outcome

Many types of cancer become drug resistant, making them difficult to treat. Researchers with University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to selectively sensitize certain cancer cells to radiation therapy that may improve tumor control and reduce treatment-related side effects. In a paper published in Nature …

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Genetic targets in Colorectal Cancer: role of KRAS, MEK and TAK1 genes Identified.

Researchers from Boston University School of Medicine have discovered a possible strategy to treat colon cancers that are caused by the mutant KRAS gene, which is responsible for approximately half of all colon cancer cases. The findings, which appear online in the journal Molecular Cancer Research, may lead to better therapeutic agents to treat this …

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Research indicates role of protein c-Cbl in Colorectal Cancer

The discovery, published online by Oncotarget journal, may lead to new therapies in managing patients with Colorectal Cancer (CRC). CRC is a complex disease caused by several genetic mutations and their consequences. In more than 80-percent of CRC patients, some of these mutations can lead to an increase in ?-catenin, a vital protein, leading to …

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NIH panel discuss roadmap for advancing research to prevent youth suicide.

An independent panel convened by the National Institutes of Health has developed a 10-year roadmap for advancing research to prevent youth suicide. To help close research gaps related to youth suicide and to assess the scientific evidence, NIH convened the Pathways to Prevention Workshop on March 29-30, 2016. The report includes recommendations to address these …

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Gut bacteria boost chemotherapy drugs in a research trial

Two bacterial species that inhabit the human gut activate immune cells to boost the effectiveness of a commonly prescribed anticancer drug, researchers report in Immunity.The study identifies a new role for Enterococcus hirae and Barnesiella intestinihominis in activating cancer-fighting T cell immune responses, thereby enhancing the effects of the chemotherapy drug cyclophosphamide. “The anti-cancer drug’s …

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Mapping recurrent prostate cancer using C-11 choline PET and multiprarmetric MRI

A team of Mayo Clinic researchers has, for the first time, successfully mapped patterns of prostate cancer recurrence, following surgery. Using C-11 choline PET imaging and multiparametric MRI, researchers found an anatomically diverse pattern of recurrence, which may help optimize treatment of patients whose prostate cancer returns after surgery. The research findings are published today …

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New vaccine targets found for Plasmodium vivax Malaria

Thousands died and more than 13 million people fell ill with malaria caused by the parasite Plasmodium vivax last year. There is no vaccine for the disease, partly because multiple strains of P. vivax circulate globally, making it difficult to develop a vaccine. Now, researchers studying a protein crucial for the parasite’s survival have found …

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Research shows girls with ADHD are at higher risk for other mental health issues.

Girls with attention deficit hyperactivity disorder are at higher risk than girls without ADHD for multiple mental disorders that often lead to cascading problems such as abusive relationships, teenage pregnancies, poor grades and drug abuse, UCLA psychologists report in the journal Pediatrics. The researchers, who conducted by far the most comprehensive analysis of girls and …

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Sleep Deprivation in children affects brain myelin development

Sleep is vital for humans. If adults remain awake for longer than usual, the brain responds with an increased need for deep sleep. In adults, these deep-sleep waves are most pronounced in the prefrontal cortex – the brain region which plans and controls actions, solves problems and is involved in the working memory. Sleep deprivation …

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