Antibiotics

New strategy to reduce antibiotic resistance using an extracellular polymeric substance inhibitor

Researchers from KU Leuven in Belgium have developed a new antibacterial strategy that weakens bacteria by preventing them from cooperating. The researchers showed that blocking slime (extracellular polymeric substance) production of salmonella bacteria weakens the bacterial community, making it easier to remove. They used a chemical, antibacterial substance 2-cyclopentenyl-5-(4-chlorophenyl)-2-aminoimidazole, a specific member of the class …

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Antibiotics versus surgery in acute appendicitis

A systemic review of research literature by scientists at the University of Southampton shows that antibiotics may be an effective treatment for acute non-complicated appendicitis in children, instead of surgery. The research paper is published in Pediatrics. The condition, which causes the appendix – a small organ attached to the large intestine – to become inflamed due to a …

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Research shows reduced Surgical Site Infections with use of Antimicrobial Sutures

New analyses of the published clinical studies indicate that antimicrobial sutures are effective for preventing surgical site infections (SSIs), and they can result in significant cost savings. The results are published in the British Journal of Surgery. In one analysis that included 21 randomized clinical trials, investigators found a risk of 138 surgical site infections …

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Research unveils structure of crucial bacterial cell wall protein

Duke University researchers have provided the first close-up glimpse of a protein, called MurJ, which is crucial for building the bacterial cell wall and protecting it from outside attack. The research is published in Nature Structural and Molecular Biology. Researchers at Duke University solved the structure of an enzyme that is crucial for helping bacteria …

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New electrochemical biosensor system that can be used for point-of-care antibiotic testing could usher personalized antibiotic treatment

A team of researchers from the University of Freiburg has developed a system inspired by biology that can detect several different antibiotics in human blood or other fluids at the same time. This biosensor system could be used for medical diagnostics in the future, especially for point-of-care testing in doctors’ practices, on house calls and …

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