Stimulated Raman Histology and Machine learning provides an alternative approach in brain tumor diagnosis

The study published in Nature Medicine examined the diagnostic accuracy of brain tumor image classification through artificial intelligence tool, compared with the accuracy of pathologist interpretation of conventional histologic images. The results for both methods were comparable: the artificial intelligence based diagnosis was 94.6% accurate, compared with 93.9% for the traditional pathologist-based assessment and interpretation. … Continue reading Stimulated Raman Histology and Machine learning provides an alternative approach in brain tumor diagnosis

Malaria drug Chloroquine helps fight treatment resistant brain cancer

After her brain cancer became resistant to chemotherapy and then to targeted treatments, 26-year-old Lisa Rosendahl's doctors gave her only a few months to live. Now a paper published in the journal eLife describes a new drug combination that has stabilized Rosendahl's disease and increased both the quantity and quality of her life: Adding the … Continue reading Malaria drug Chloroquine helps fight treatment resistant brain cancer

Piperlongumine, chemical from Indian pepper plant inhibits enzyme in cancer cells

UT Southwestern Medical Center scientists have uncovered the chemical process behind anti-cancer properties of a spicy Indian pepper plant called the long pepper, whose suspected medicinal properties date back thousands of years. The study is published in the Journal of Biological Chemistry.Dr. Westover's lab used X-ray crystallography to create this molecular model of piperlongumine.Credit: UT … Continue reading Piperlongumine, chemical from Indian pepper plant inhibits enzyme in cancer cells

New biomarker based on expression of SHOX2 gene for predicting survival in Gliomas

Researchers at UT Southwestern Medical Center have found a new biomarker for glioma, a common type of brain cancer, that can help doctors determine how aggressive a cancer is and that could eventually help determine the best course of treatment. The findings are published in EBiomedicine. Researchers from the Harold C. Simmons Comprehensive Cancer Center found … Continue reading New biomarker based on expression of SHOX2 gene for predicting survival in Gliomas