Cancer-proteins

Multi drug resistant cancer is associated with loss of TP53TG1 molecule

A new study by researchers at the Bellvitge Biomedical Research Institute (IDIBELL) has found a cause of multiple resistance in cancer chemotherapy. They discovered that 10% of colon and stomach tumors present wit loss of a molecule called TP53TG1. The functionof TP53TG1 is to prevent activation of YBX1 protein. Without surveillance of TP53TG1 in these …

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Research identifies protein behind side effects of cellular senescence

Cellular senescence is a state in which normal healthy cells do not have the ability to divide. Senescence can occur when cancer-causing genes are activated in normal cells or when chemotherapy is used on cancer cells. Thus, senescence induces a mechanism that halts the growth of rapidly dividing cells. Once thought to only be beneficial …

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