Biomarker Autotaxin, related to diabetes predicts Alzheimer’s disease outcome

An enzyme found in the fluid around the brain and spine is giving researchers a snapshot of what happens inside the minds of Alzheimer's patients and how that relates to cognitive decline.Iowa State University researchers say higher levels of the enzyme, autotaxin, significantly predict memory impairment and Type 2 diabetes.  Autotaxin often studied in cancer … Continue reading Biomarker Autotaxin, related to diabetes predicts Alzheimer’s disease outcome

Virtual clinical trials use mathematical modelling to predict melanoma response

Researchers from Moffitt Cancer Center's Integrated Mathematical Oncology (IMO) Department are overcoming the limitations of common preclinical experiments and clinical trials by studying cancer through mathematical modeling. A study led by Alexander "Sandy" Anderson, Ph.D., chair of IMO, and Eunjung Kim, Ph.D., an applied research scientist, shows how mathematical modeling can accurately predict patient responses … Continue reading Virtual clinical trials use mathematical modelling to predict melanoma response

Medical device that activates heat shock response found helpful in Diabetic patients

Although effective for the treatment of diabetes, exercise is sometimes difficult for overweight or elderly people. A new wearable medical device developed by Kumamoto University has been found to effect visceral fat loss and improve blood glucose (sugar). The current study reports clinical trial results for optimal use frequency.Type 2 diabetes is a disease of … Continue reading Medical device that activates heat shock response found helpful in Diabetic patients

Research finds bi-directional association between fatty liver disease and heart disease

Researchers have shown that a bi-directional relationship exists between fatty liver disease and cardiovascular disease. Fatty liver disease can lead to increased cardiovascular disease risk and vice versa. The findings, which appear in the Journal of Hepatology, are important in understanding the link between fatty liver disease and cardiovascular disease, which continues to be one … Continue reading Research finds bi-directional association between fatty liver disease and heart disease

Research shows advances in development of hand held breathalyzers to diagnose Diabetes

For several years, scientists have been working toward "breathalyzers" that can diagnose various diseases without painful pinpricks, needles or other unpleasant methods. Now, one team has developed a new, portable breath analyzer that could someday help doctors diagnose diabetes noninvasively in the office. The report appears in the ACS journal Analytical Chemistry.Many studies examining the … Continue reading Research shows advances in development of hand held breathalyzers to diagnose Diabetes

HIV treatment with immunotherapy using VRC01 shows promise and limitations

Immunotherapy has revolutionized treatment options in oncology, neurology, and many infectious diseases and now there is fresh hope that the same method could be used to treat or functionally cure HIV, according to two related studies from Perelman School of Medicine at the University of Pennsylvania, the University of Alabama at Birmingham (UAB), and the … Continue reading HIV treatment with immunotherapy using VRC01 shows promise and limitations

Gene therapy with Alipogene Tiparvovec (Glybera) for Lipoprotein Lipase Deficiency shows promise

Over a 6-year period, patients with the genetic disease lipoprotein lipase deficiency (LPLD) who received a single gene therapy treatment of alipogene tiparvovec had a marked reduction in the severity and frequency of pancreatitis. No cases of severe pancreatitis and only one admission to the intensive care unit for an lipoprotein lipase deficiency related abdominal … Continue reading Gene therapy with Alipogene Tiparvovec (Glybera) for Lipoprotein Lipase Deficiency shows promise