Biomarker Autotaxin, related to diabetes predicts Alzheimer’s disease outcome

An enzyme found in the fluid around the brain and spine is giving researchers a snapshot of what happens inside the minds of Alzheimer's patients and how that relates to cognitive decline.Iowa State University researchers say higher levels of the enzyme, autotaxin, significantly predict memory impairment and Type 2 diabetes.  Autotaxin often studied in cancer … Continue reading Biomarker Autotaxin, related to diabetes predicts Alzheimer’s disease outcome

Multiple sclerosis pathogenesis: association between amount of leaked hemoglobin and severity of brain shrinkage

A leak of a protein called hemoglobin from damaged red blood cells may be associated with brain shrinkage in multiple sclerosis. This is the conclusion of a team from Imperial College London, whose early-stage findings suggest treatments that lower levels of hemoglobin could slow progression of the disease. Haemoglobin carries iron and oxygen around the … Continue reading Multiple sclerosis pathogenesis: association between amount of leaked hemoglobin and severity of brain shrinkage

Trastuzumab biosimilar (MYL-14010) shown effective in breast cancer clinical trial

Among women with metastatic breast cancer, treatment with a drug that is biosimilar to the breast cancer drug trastuzumab resulted in an equivalent overall response rate at 24 weeks compared with trastuzumab, according to a study published online by JAMA.Trstuzumab BiosimilarsBiological agents, including monoclonal antibodies, have increased the treatment options and greatly improved outcomes for … Continue reading Trastuzumab biosimilar (MYL-14010) shown effective in breast cancer clinical trial

Walnut consumption is key to better mood and happiness in college students

Professor Pribis recommends a handful of walnuts, 1 to 3 ounces,daily for increased health benefits. The benefits from the tree nut not only positively affect mood but also the cardiovascularsystem and can be used as a support for weight loss.Credit: California Walnut CommissionCollege can be a stressful time for young adults as they figure out how … Continue reading Walnut consumption is key to better mood and happiness in college students

Virtual clinical trials use mathematical modelling to predict melanoma response

Researchers from Moffitt Cancer Center's Integrated Mathematical Oncology (IMO) Department are overcoming the limitations of common preclinical experiments and clinical trials by studying cancer through mathematical modeling. A study led by Alexander "Sandy" Anderson, Ph.D., chair of IMO, and Eunjung Kim, Ph.D., an applied research scientist, shows how mathematical modeling can accurately predict patient responses … Continue reading Virtual clinical trials use mathematical modelling to predict melanoma response

Protein biomarkers to screen early type 1 diabetes mellitus

Certain proteins in the blood of children can predict incipient type 1 diabetes, even before the first symptoms appear. A team of scientists at the Helmholtz Zentrum München, partners in the German Center for Diabetes Research (DZD), reported these findings in the ‘Diabetologia’ journal.The work was based on two large studies that are intended to … Continue reading Protein biomarkers to screen early type 1 diabetes mellitus

Bone marrow derived stem cell therapy shown to reduce inflammation in traumatic brain injury

Results of a cellular therapy clinical trial for traumatic brain injury (TBI) using a patient's own stem cells showed that the therapy appears to dampen the body's neuroinflammatory response to trauma and preserve brain tissue, according to researchers at The University of Texas Health Science Center at Houston (UTHealth). The results, which also confirmed safety … Continue reading Bone marrow derived stem cell therapy shown to reduce inflammation in traumatic brain injury