Drug-Development

New body-on-a-chip technology to advance pharmacological research

Researchers from MIT have developed “physiome on chip” technology that could be used to evaluate new drugs and detect side effects before the drugs are tested in human clinical trials. This could be used an alternative to animal testing for pharmacological testing before human clinical trials. Body on a chip. Credit: Felice Frankel They used …

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Dynamic undocking, a new computational method for efficient drug research

Researchers of the University of Barcelona have developed a more efficient computational method to identify new drugs. The study, published in the scientific journal Nature Chemistry, proposes a new way of facing the discovery of molecules with biological activity.Researchers devised dynamic undocking (DUck), a fast computational method to calculate the work necessary to reach a …

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fABMACS – a new computational tool to simulate drug protein interaction

A new computational tool called fABMACS is helping scientists see beyond static images of proteins to more efficiently understand how these molecules function, which could ultimately speed up the drug discovery process. Simulation of BRD4 interacting with a potent inhibitor. Credit: Dr. Bradley Dickson, Rothbart Laboratory Van Andel Research Institute “The goal of targeted drug …

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