Liver disease

New plant based compounds show promise for hepatitis B

Researchers have found that certain plant-derived products may help prevent and treat hepatitis B virus (HBV) infection. Proanthocyanidin (PAC) and its analogs, oolonghomobisflavanes, act by inhibiting viral entry into host cells. The life cycle of Hepatitis B Virus. Credit Dr. Graham Colm Wikipedia The investigators noted that PAC was effective even against treatment-resistant HBV strains, …

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Researcher discover role of protein CPEB4 in development of fatty liver

The scientists at IRB Barcelona discovered the role of a protein CPEB4 in the pathogenesis of nonalcoholic steatohepatitis (fatty liver). This condition generally leads to chronic inflammation, which can trigger fibrosis, cirrhosis and ultimately liver cancer. This study paves the way to examine therapeutic strategies to fight and prevent this disease. The results of the …

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New approach to treating non-alcoholic fatty liver disease

Researchers from the University of South Carolina, Duke University, the University of Alabama at Birmingham, and Metabolon Inc. Research Triangle Park has discovered a new pathway in the liver that opens the door to treating non-alcoholic fatty liver disease, a condition that affects up to 25 percent of the population and may lead to cirrhosis …

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Research finds bi-directional association between fatty liver disease and heart disease

Researchers have shown that a bi-directional relationship exists between fatty liver disease and cardiovascular disease. Fatty liver disease can lead to increased cardiovascular disease risk and vice versa. The findings, which appear in the Journal of Hepatology, are important in understanding the link between fatty liver disease and cardiovascular disease, which continues to be one …

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Researchers developed method of determining liver disease with blood tests

A new non-invasive method of predicting the risk of developing a severe form of liver disease could ensure patients receive early and potentially life-saving medical intervention before irreversible damage is done. Using information collected in a liver biopsy study, researchers at Cardiff University have developed a method of determining the onset of non-alcoholic steatohepatitis (NASH) …

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