Molecular-Medicine

Quantum dot technology to advance molecular cell imaging

Researchers from the University of Illinois at Urbana-Champaign bioengineering team and Mayo Clinic have engineered a new type of molecular probe that can measure and count RNA in cells and tissue without organic dyes. The probe is based on the conventional fluorescence in situ hybridization (FISH) technique, but it relies on compact quantum dots to …

Quantum dot technology to advance molecular cell imaging Read More »

Understanding molecular mechanisms behind germinal matrix hemorrhage

Researchers have utilized a mouse model to determine the molecular mechanisms underlying germinal matrix hemorrhage. Nearly 12,000 premature infants born annually in the US are affected by neonatal brain hemorrhage which results in mortality and long-term morbidity. Unfortunately, no treatment exists for this condition, and the only preventive measure is steroids before birth, which has …

Understanding molecular mechanisms behind germinal matrix hemorrhage Read More »

The role of PRC2 in controlling gene activity in human stem cells.

Researchers at the Babraham Institute have revealed a new understanding of the molecular switches that control gene activity in human embryonic stem cells. In the developing embryo and during the specialisation of stem cells, the activity of genes must be tightly controlled so that the correct genes are switched on and off at the right …

The role of PRC2 in controlling gene activity in human stem cells. Read More »

Calorie restriction and cellular aging process

Recent research published in Molecular & Cellular Proteomics offers one glimpse into how cutting calories impacts aging inside a cell. The researchers found that when ribosomes – the cell’s protein makers – slow down, the aging process slows too. The decreased speed lowers production but gives ribosomes extra time to repair themselves. Repairing individual parts …

Calorie restriction and cellular aging process Read More »

Analysis of interactome of Zika virus infected neural cells shows altered expression of more than 500 proteins

Zika virus (ZIKV) interferes with the cellular machinery controlling cell division and alters the expression of hundreds of genes responsible for guiding the formation and development of brain cells, according to findings of research published in Scientific Reports. Zika virus structure. Credit: Wikipedia / David Goodwill The association between Zika virus (ZIKV) infection and microcephaly has …

Analysis of interactome of Zika virus infected neural cells shows altered expression of more than 500 proteins Read More »

Research in mice shows molecular mechanism underlying Oxycodone addiction

RGS9-2, a key signaling protein in the brain known to play a critical role in the development of addiction-related behaviors, acts as a positive modulator of oxycodone reward in both pain-free and chronic pain states, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published in the journal Neuropsychopharmacology. …

Research in mice shows molecular mechanism underlying Oxycodone addiction Read More »