Nanoparticles

New technology to monitor chemotherapy using magnetic nanoparticles

Researchers from Michigan State University propose a novel non-invasive magnetic particle imaging (MPI) to monitor chemotherapy release in vivo. This method employs superparamagnetic nanoparticles as the contrast agent to monitor drug release in the body. In this study researchers designed iron oxide nanocomposite loaded with a chemotherapy drug doxorubicin which serves as a drug delivery …

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Gene therapy using lipid based nanoparticles

Lipid nanoparticles (SLNs and NLCs) are regarded as highly promising systems for delivering nucleic acids in gene therapy. Literature review by researchers at PharmaNanoGene describes these systems and their main advantages in gene therapy, such as their capacity to protect the gene material against degradation, to facilitate cell and nucleus internalization and to boost the transfection process. View …

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Large synthetic nanoparticles mimic biomolecules

Chemists at Carnegie Mellon University have demonstrated that synthetic nanoparticles can achieve the same level of structural complexity, hierarchy and accuracy as their natural counterparts biomolecules. The study, published in Science, also reveals the atomic-level mechanisms behind nanoparticle self-assembly. The structure of the largest gold nanoparticle to-date, Au246(SR)80, was resolved using x-ray crystallography. Credit: Rongchao …

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New approach to treating cancer with therapeutic short interfering RNA (siRNA) delivered by nanohydrogel nanoparticles

A novel targeted therapy using nanoparticles has enabled researchers at the Georgia Institute of Technology to purge ovarian tumors in limited, in vivo tests in mice. “The dramatic effect we see is the massive reduction or complete eradication of the tumor, when the ‘nanohydrogel’ treatment is given in combination with existing chemotherapy,” said chief researcher …

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Nanomedicine: Nanotechnology and Nanoscience for better health

Nanoscience research involves molecules that are tiny compared to the size of cancer cells and that have the potential to profoundly improve the quality of our health and our lives. Now nine prominent Nano scientists look ahead to what we can expect in the coming decade, and conclude that nanoscience is poised to make important contributions in …

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Researchers focus on using Nanoparticles to improve drug delivery in HIV patients

New research led by the University of Liverpool aims to improve the administration and availability of drug therapies to HIV patients through the use of nanotechnology.  The research, conducted by the collaborative nanomedicine research programme led by Pharmacologist Professor Andrew Owen and Materials Chemist Professor Steve Rannard, examined the use of nanotechnology to improve the …

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Nanoparticle injections minimize inflammation following cartilage injury

Osteoarthritis is a debilitating condition that affects at least 27 million people in the United States, and at least 12 percent of osteoarthritis cases stem from earlier injuries. Over-the-counter painkillers, such as anti-inflammatory drugs, help reduce pain but do not stop unrelenting cartilage destruction. Consequently, pain related to the condition only gets worse. Now, researchers …

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