Nanotechnology

A new approach to create targeted nanovesicles for cancer treatment

Researchers have used autologous immune cells from the mouse to create nanovesicles to be used in the delivery of drugs to tumors. This technique helped them to create a sufficient number of nanovesicles inexpensively to be used as drug delivery system. This image shows ligands-grafted extracellular vesicles as drug delivery vehicles.Credit: Xin Zou  Cells naturally …

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New nanosensor technology to detect osteoarthritis biomarker

Researchers at Wake Forest Baptist Medical Center have been able to analyze hyaluronic acid using solid-state nanopore sensor. This technique allows them to study its role in osteoarthritis and other inflammatory joint disorders. This technique is first of a kind and is a significant improvement regarding relative ease to perform and high precision from other …

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Gene therapy using lipid based nanoparticles

Lipid nanoparticles (SLNs and NLCs) are regarded as highly promising systems for delivering nucleic acids in gene therapy. Literature review by researchers at PharmaNanoGene describes these systems and their main advantages in gene therapy, such as their capacity to protect the gene material against degradation, to facilitate cell and nucleus internalization and to boost the transfection process. View …

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Large synthetic nanoparticles mimic biomolecules

Chemists at Carnegie Mellon University have demonstrated that synthetic nanoparticles can achieve the same level of structural complexity, hierarchy and accuracy as their natural counterparts biomolecules. The study, published in Science, also reveals the atomic-level mechanisms behind nanoparticle self-assembly. The structure of the largest gold nanoparticle to-date, Au246(SR)80, was resolved using x-ray crystallography. Credit: Rongchao …

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Development of thin-film biomaterials using nanofibres to be used as scaffolding for bone regeneration

In future, it may be possible to use nanofibres to improve the attachment of bone implants, or the fibres may be used directly to scaffold bone regeneration. This would aid the healing of fractures and may enable the care of osteoporosis. This is detailed in a new dissertation. Hydroxyapatite nanofibre film produced at the University …

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Liquid biopsy chip based on carbon nano-tubes to detect circulating cancer cells

A chip developed by mechanical engineers at Worcester Polytechnic Institute (WPI) can trap and identify metastatic cancer cells in a small amount of blood drawn from a cancer patient. The breakthrough technology uses a simple mechanical method that has been shown to be more effective in trapping cancer cells than the microfluidic approach employed in …

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MESO-BRAIN stem cell research project to develop 3D nanoprinting techniques to replicate neural networks

Aston University heading up major €3.3m stem cell research project to develop 3D nanoprinting techniques that could replicate brain’s neural networks. Aston University has launched MESO-BRAIN, a major stem cell research project which it hopes will develop three-dimensional (3D) nanoprinting techniques that can be used to replicate the brain’s neural networks. The cornerstone of the …

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Nanomedicine: Nanotechnology and Nanoscience for better health

Nanoscience research involves molecules that are tiny compared to the size of cancer cells and that have the potential to profoundly improve the quality of our health and our lives. Now nine prominent Nano scientists look ahead to what we can expect in the coming decade, and conclude that nanoscience is poised to make important contributions in …

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Researchers focus on using Nanoparticles to improve drug delivery in HIV patients

New research led by the University of Liverpool aims to improve the administration and availability of drug therapies to HIV patients through the use of nanotechnology.  The research, conducted by the collaborative nanomedicine research programme led by Pharmacologist Professor Andrew Owen and Materials Chemist Professor Steve Rannard, examined the use of nanotechnology to improve the …

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