Neuroscience

Scientists identify neural pathways behind visual perceptual decision-making

Scientists at the National Eye Institute (NEI) have found that neurons in the superior colliculus are key players in allowing us to detect visual objects and events. This structure doesn’t help us recognize what the specific object or event is; instead, it’s the part of the brain that decides something is there at all.  In …

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Potential treatment for Alzheimer’s dementia using cell therapy

Researchers from Gladstone Institute uncovered the therapeutic benefits of genetically improving interneurons with a voltage-gated sodium channel Nav1.1 and transplanting them into the brain of a mouse model of Alzheimer’s disease. This study is led by Jorge Palop, Ph.D., an assistant investigator at the Gladstone Institutes. The study findings are published in journal Neuron. Inhibitory …

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Researchers find possible link between autism and nuclear receptor protein LXRβ

Research by University of Houston scientists discovered a possible link between nuclear receptor protein LXRβ (Liver X receptor Beta) and autism spectrum disorder. They found that nuclear receptor LXRβ deletion causes poor development of dentate gyrus, a part of brain’s hippocampus. The dentate gyrus, or DG, is responsible for emotion and memory and is known …

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A new algorithm to solve memory problems in large-scale human brain simulations

 Researchers have come closer towards advancing technology to create computer simulations of the brain networks using exascale-class supercomputers. Their findings are published in journal  Frontiers in Neuroinformatics. Credit: Forschungszentrum Jülich The human brain is a complex network composed of approximately 100 billion neurons. With current computing power, it is impossible to simulate 100 percent working brain. …

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Effects of flu on brain

Group of researchers from Germany and USA studied effects of influenza virus on brain cells. The study published in the Journal of Neuroscience finds that female mice infected with two different strains of the flu shows changes in structure and function of the hippocampus. These changes persist for one month after infection. The long-term effect …

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Peripheral vision reaction time assessment to diagnose mild traumatic brain injury patients

A new test using peripheral vision reaction time could lead to earlier diagnosis and more effective treatment of mild traumatic brain injury, often referred to as a concussion, according to Peter J. Bergold, PhD, professor of physiology and pharmacology at SUNY Downstate Medical Center and corresponding author of a study published by the Journal of Neurotrauma. While …

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New approach to Multiple Sclerosis treatment using immunosuppression and stem cells shows promise

New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person’s own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS). Five years after receiving the treatment, called high-dose immunosuppressive therapy and autologous hematopoietic cell transplant (HDIT/HCT), 69 percent of trial participants had survived without experiencing progression …

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Research shows positive outcome for early epilepsy surgery

There are important, long-term gains from hastening the processes around surgical interventions against epilepsy, before the disease has had too much negative impact on brain functions and patients’ lives. These are some of the findings of a thesis for which more than 500 patients were studied and followed up. “Around one third of those undergoing …

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Analysis of interactome of Zika virus infected neural cells shows altered expression of more than 500 proteins

Zika virus (ZIKV) interferes with the cellular machinery controlling cell division and alters the expression of hundreds of genes responsible for guiding the formation and development of brain cells, according to findings of research published in Scientific Reports. Zika virus structure. Credit: Wikipedia / David Goodwill The association between Zika virus (ZIKV) infection and microcephaly has …

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