Online depression intervention tool found effective in adolescent mothers

Researchers from the University of Louisville found that using an Internet-based depression intervention tool program found effective in improving treatment rates of adolescent depressed mothers. This study is published in journal Archives of Women's Mental Health.Roughly half of the 400,000 adolescents 18 and younger who give birth annually in the United States experience depressive symptoms, but less … Continue reading Online depression intervention tool found effective in adolescent mothers

Potential treatment for Alzheimer’s dementia using cell therapy

Researchers from Gladstone Institute uncovered the therapeutic benefits of genetically improving interneurons with a voltage-gated sodium channel Nav1.1 and transplanting them into the brain of a mouse model of Alzheimer's disease. This study is led by Jorge Palop, Ph.D., an assistant investigator at the Gladstone Institutes. The study findings are published in journal Neuron.Inhibitory interneurons … Continue reading Potential treatment for Alzheimer’s dementia using cell therapy

Researchers find possible link between autism and nuclear receptor protein LXRβ

Research by University of Houston scientists discovered a possible link between nuclear receptor protein LXRβ (Liver X receptor Beta) and autism spectrum disorder. They found that nuclear receptor LXRβ deletion causes poor development of dentate gyrus, a part of brain's hippocampus. The dentate gyrus, or DG, is responsible for emotion and memory and is known … Continue reading Researchers find possible link between autism and nuclear receptor protein LXRβ

New target receptor for treating depression GPR158

Researchers from the Scripps Research Institute find a new target receptor called GPR158 for treating depression. Their research shows that individuals with high levels of above receptor may be more susceptible to depression following chronic stress."The next step in this process is to come up with a drug that can target this receptor," says Kirill Martemyanov, … Continue reading New target receptor for treating depression GPR158

Diets rich in fruits and vegetables associated with lower depression risk

People who eat vegetables, fruit and whole grains may have lower rates of depression over time, according to a preliminary study that will be presented at the American Academy of Neurology's 70th Annual Meeting.Research found that people whose diets adhered more closely to the Dietary Approaches to Stop Hypertension (DASH) diet were less likely to … Continue reading Diets rich in fruits and vegetables associated with lower depression risk

People with depression found to have low arginine levels

Researchers from the University of Eastern Finland have shown that people suffering from major depressive disorder have reduced arginine levels. One of the role of arginine in body is to produce nitric oxide, which in turn have role in vascular regulation and is a nervous system and immune defence mediator. The global arginine bioavailability ratio … Continue reading People with depression found to have low arginine levels

Adults with autism spectrum disorder showed good results with cognitive enhancement therapy compared to enriched supportive therapy

While there have been advances in early detection and many studies involving the treatment of children with autism spectrum disorder (ASD), few efforts to date have focused on interventions for adults. These individuals experience significant challenges throughout adulthood, including unemployment, social impairment and poor quality of life. It is believed that the challenges people with … Continue reading Adults with autism spectrum disorder showed good results with cognitive enhancement therapy compared to enriched supportive therapy

Role of diet and gut microbiome in the major depressive disorder

An international group of researchers headed by André Carvalho has published in Psychotherapy and Psychosomatic a paper that provides new data and prospects for the links between the intestinal flora and several disorders, notably depression.Persistent low-grade immune-inflammatory processes, oxidative and nitrosative stress and hypothalamic-pituitary-adrenal axis activation are integral to the pathophysiology of the major depressive … Continue reading Role of diet and gut microbiome in the major depressive disorder

Stress, cortisol and perceptual learning process

Neuroscientists of the Ruhr University Bochum found that stress has adverse impact on our learning process. Usually when we train our senses, we sharpen them and thereby improve our perceptual performance. However during stressful situations we produce a hormone called cortisol, which completely blocks this important ability. These findings are reported in Journal “Psychoneuroendocrinology” Stress by … Continue reading Stress, cortisol and perceptual learning process

Research uncovers link between long-term opioid use and preexisting psychiatric and behavioral disease

A wide range of pre-existing psychiatric and behavioral conditions and the use of psychoactive drugs could be important risk factors leading to long-term use of opioid pain medications, reports a study in Journal Pain, the official publication of the International Association for the Study of Pain (IASP).Using a nationwide insurance database, the researchers identified 10.3 … Continue reading Research uncovers link between long-term opioid use and preexisting psychiatric and behavioral disease