Regenerative-Medicine

Age-related macular degeneration treated with a stem cell retinal patch

Researchers developed retinal eye patch made from human embryonic stem cells to treat age-related macular degeneration. Researchers grew retinal pigment epithelial cells from stem cells and used synthetic basement membrane to create a retinal patch. Phase 1 clinical trial findings are reported in the journal Nature Biotechnology. Age-related macular degeneration is the most common cause of visual impairment in …

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Understanding interaction between heart muscle cells and nanoscaffoding

Researchers from Moscow Institute of Physics and Technology (MIPT) have researched nanofibrous scaffold structure and its interaction with rat heart muscle cells.  This study revealed that cardiac muscle cells envelop nanofibers as they grow, but fibroblasts tend to spread out on fibers forming several focal adhesion sites. Nanofibers enveloped by Heart muscle cells. The 3-D …

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Calorie restricted diet promotes intestinal regeneration after injury

Dramatic calorie restriction have long been known to boost healthy lifespan and reduce the risk of heart attack, diabetes and other age-related conditions. In animal studies it is shown to extend life span in most animal species examined. Further research has shown that animals fed restricted-calorie diets are also better able to regenerate numerous tissues …

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Functioning human kidney tissue produced from stem cells.

Scientists have successfully produced human kidney tissue within a living organism which is able to produce urine. The study led by Professors Sue Kimber and Adrian Woolf from The University of Manchester, signifies a significant milestone in the development of treatment for kidney disease.This research is published in the journal Stem Cell Reports. Kidney glomeruli  …

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Clinical trial shows feasibility of lung regeneration using stem cells

A research team from Tongji University in China have made a breakthrough in human lung regeneration technology. Researchers have regenerated patients’ damaged lungs using autologous lung stem cell transplantation in a pilot clinical trial. The study results are published in journal Protein & Cell. In 2015, Professor Zuo and his colleagues identified p63+/Krt5+ adult stem …

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Vitamins A and Vitamin C help erase epigenetic memory held by cells

Vitamins A and C aren’t just good for your health, they affect your DNA too. Researchers at the Babraham Institute and their international collaborators have discovered how vitamins A and C act to modify the epigenetic ‘memory’ held by cells; insight which is significant for regenerative medicine and our ability to reprogramme cells from one …

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