Protein galectin-3 plays role in insulin resistance and glucose intolerance

By removing the protein galectin-3 (Gal3), a team of investigators led by University of California School of Medicine researchers were able to reverse diabetic insulin resistance and glucose intolerance in mouse models of obesity and diabetes.By binding to insulin receptors on cells, Gal3 prevents insulin from attaching to the receptors resulting in cellular insulin resistance. … Continue reading Protein galectin-3 plays role in insulin resistance and glucose intolerance

Glioblastoma’s dependence of cholesterol from astrocytes, a possible new therapeutic target

Researchers at University of California San Diego School of Medicine, Ludwig Institute for Cancer Research and The Scripps Research Institute, with colleagues in Los Angeles and Japan, report that depriving deadly brain cancer cells of cholesterol, which they import from neighboring healthy cells, specifically kills tumor cells and caused tumor regression and prolonged survival in … Continue reading Glioblastoma’s dependence of cholesterol from astrocytes, a possible new therapeutic target