Virus

Computational model uncovers progression of HIV infection in brain

University of Alberta research team successfully uncovered the progression of HIV infection in the brain using a new mathematical model. The team is utilizing this model to develop a nasal spray to administer  antiretroviral medication effectively. Their research is published in Journal of Neurovirology. Research was done by PhD student Weston Roda and Prof. Michael …

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Researchers identify how Ebola virus disables the human immune system

A research study by scientists at the University of Texas Medical Branch in Galveston sheds light on how Ebola effectively disables the human immune system. Virologist Alex Bukreyev, UTMB professor and senior author of the study, said the research team engineered versions of the Ebola virus in order to understand its effects on immune system. The …

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Analysis of interactome of Zika virus infected neural cells shows altered expression of more than 500 proteins

Zika virus (ZIKV) interferes with the cellular machinery controlling cell division and alters the expression of hundreds of genes responsible for guiding the formation and development of brain cells, according to findings of research published in Scientific Reports. Zika virus structure. Credit: Wikipedia / David Goodwill The association between Zika virus (ZIKV) infection and microcephaly has …

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New plant based compounds show promise for hepatitis B

Researchers have found that certain plant-derived products may help prevent and treat hepatitis B virus (HBV) infection. Proanthocyanidin (PAC) and its analogs, oolonghomobisflavanes, act by inhibiting viral entry into host cells. The life cycle of Hepatitis B Virus. Credit Dr. Graham Colm Wikipedia The investigators noted that PAC was effective even against treatment-resistant HBV strains, …

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Researchers use computer simulation to understand structure of virus

(Pittsburg) Researchers led by Carnegie Mellon University physicist Markus Deserno and University of Konstanz (Germany) chemist Christine Peter have developed a computer simulation that crushes viral capsids. By allowing researchers to see how the tough shells break apart, the simulation provides a computational window for looking at how viruses and proteins assemble. The study is …

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