Zika-virus

Research shows efficacy of malarial drug Chloroquine in treating Zika infection

Zika virus remains a major global health risk. In most adults, Zika causes mild flu-like symptoms. But in pregnant women, the virus can cause serious birth defects in babies including microcephaly a neurological condition in which newborns have unusually small heads and fail to develop properly. There is no treatment or way to reverse the …

Research shows efficacy of malarial drug Chloroquine in treating Zika infection Read More »

Analysis of interactome of Zika virus infected neural cells shows altered expression of more than 500 proteins

Zika virus (ZIKV) interferes with the cellular machinery controlling cell division and alters the expression of hundreds of genes responsible for guiding the formation and development of brain cells, according to findings of research published in Scientific Reports. Zika virus structure. Credit: Wikipedia / David Goodwill The association between Zika virus (ZIKV) infection and microcephaly has …

Analysis of interactome of Zika virus infected neural cells shows altered expression of more than 500 proteins Read More »

Zika virus research: Structure of immature virus revealed

Researchers at Purdue University have determined the high-resolution structure of immature Zika virus, a step toward better understanding how the virus infects host cells and spreads. Purdue researchers have determined the high-resolution structure of the immature Zika virus. This composite image of the surface (left), and cross-sectional region (right), reflect the new findings. Research into …

Zika virus research: Structure of immature virus revealed Read More »

Understanding how Zika virus interacts with human antibody C10 paves way for new therapeutic target

As Zika virus spreads throughout the world, the call for rapid development of therapeutics to treat Zika virus rings loud and clear. Taking a step further in identifying a possible therapeutic candidate, a team of researchers at Duke-NUS Medical School (Duke-NUS), in collaboration with scientists from the University of North Carolina, have discovered the mechanism …

Understanding how Zika virus interacts with human antibody C10 paves way for new therapeutic target Read More »

Current vaccination trials using Zika Purified Inactivated Virus (ZPIV) vaccine

The first of five early stage clinical trials to test the safety and ability of an investigational Zika vaccine candidate called the Zika Purified Inactivated Virus (ZPIV) vaccine to generate an immune system response has begun at the Walter Reed Army Institute of Research (WRAIR) Clinical Trial Center in Silver Spring, Maryland. The experimental Zika …

Current vaccination trials using Zika Purified Inactivated Virus (ZPIV) vaccine Read More »

Mathematical model suggests increase in Zika virus outbreaks following Dengue fever vaccination

Vaccinating against dengue fever could increase outbreaks of Zika, suggests new research out of York University and Xi’an Jiaotong University in China. The research identifies a potentially serious public health concern. More than a third of the world’s population lives in areas where dengue is endemic and cases of co-infection with Zika have already been …

Mathematical model suggests increase in Zika virus outbreaks following Dengue fever vaccination Read More »

Research finds effects of Zika virus on male reproductive system in mice

But a new study in mice suggests that Zika infection also may have worrisome consequences for men that interfere with their ability to have children. The research indicates that the virus targets the male reproductive system. Three weeks after male mice were infected with Zika, their testicles had shrunk, levels of their sex hormones had …

Research finds effects of Zika virus on male reproductive system in mice Read More »