Tag: Alzheimer-Disease
-
Biomarker Autotaxin, related to diabetes predicts Alzheimer’s disease outcome
An enzyme found in the fluid around the brain and spine is giving researchers a snapshot of what happens inside the minds of Alzheimer’s patients and how that relates to cognitive decline. Iowa State University researchers say higher levels of the enzyme, autotaxin, significantly predict memory impairment and Type 2 diabetes. Autotaxin often studied in…
-
Research shows Statins lower the risk of Alzheimer’s disease
The new study shows that, based on a sample of 399,979 Medicare beneficiaries, men and women who took statins two years or more lowered their risk of Alzheimer’s disease in the period spanning from 2009 to 2013. The incidence of Alzheimer’s disease was reduced for beneficiaries frequently prescribed statins (high users), compared to low users, USC…
-
Combating Aging by removing damaged mitochondrial DNA
Researchers from UCLA and Caltech have made discoveries that might help slow and potentially reverse the process of aging in cells. They generated new methods that allow identification of factors that selectively remove damaged mitochondrial DNA, which will affect the process of aging at the cellular level. Aging is, in part, due to changes in…
-
Fluselenamyl in conjuction with positron emission tomography (PET) scans shown effective in diagnosing early Alzheimer’s disease pathology
Researchers at Washington University School of Medicine in St. Louis have developed a chemical compound, named Fluselenamyl, that detects amyloid clumps better than current FDA-approved compounds. If a radioactive atom is incorporated into the compound, its location in a living brain can be monitored using positron emission tomography (PET) scans. The compound, described in a paper…
-
Study reveals potential new treatment target Nuak1 kinase to prevent accumulation of protein in early Alzheimer’s disease
Taking a pill that prevents the accumulation of toxic molecules in the brain might someday help prevent or delay Alzheimer’s disease, according to scientists at Baylor College of Medicine, Texas Children’s Hospital and Johns Hopkins University School of Medicine. The study, published today in Cell Press journal Neuron, took a three-pronged approach to help subdue…
-
Neuronal transport mechanism mutations may have a role in Alzheimer’s disease pathology
Researchers at University of California San Diego School of Medicine have confirmed that mutation-caused dysfunction in a process cells use to transport molecules within the cell plays a previously suspected but underappreciated role in promoting the heritable form of Alzheimer’s disease (AD), but also one that might be remedied with existing therapeutic enzyme inhibitors. The…
-
Understanding cause of memory loss in Tauopathies
Tauopathies are a group of neurodegenerative disorders, including Alzheimer’s disease that are characterized by the deposition of aggregates of the tau protein inside brain cells. A new study reveals that the cutting of tau by an enzyme called caspase-2 may play a critical role in the disordered brain circuit function that occurs in these diseases.…
Medical News Observer 