Alzheimer’s Dementia
Alzheimer’s dementia is characterized by a gradual decline in memory, thinking, and reasoning skills. The exact cause of Alzheimer’s is not fully understood, but it’s believed to involve a combination of genetic, environmental, and lifestyle factors. Pathologically Alzheimer’s dementia is marked by presence of tau tangles and amyloid plaques in the affected neuronal cell, leading to the death. Symptoms typically start with mild memory loss and progress to severe impairment in cognitive and functional abilities, making daily tasks and self-care challenging. Currently, there is no cure for Alzheimer’s, but therapy focuses on symptom managment and improving quality of life.
Alzheimer’s Dementia
Latest Posts
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Brain changes in diabetic patients
A new study published in Diabetologia reveals that overweight and obese individuals with early stage type 2 diabetes (T2D) had more severe and progressive abnormalities in brain structure and cognition compared to normal-weight study participants. The research conducted…
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New approach to treating dementia using antisense oligonucleotides
In a study of mice and monkeys, NIH funded researchers showed that they could prevent and reverse some of the brain injury caused by the toxic form of a protein called tau. Scientists used a designer compound to…
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Protein Wnt5a is important in sustaining adult neuron structure in mice hippocampus
Humans and other vertebrates depend on a portion of the brain called the hippocampus for learning, memory and their sense of location. Nerve cell structures in the adult hippocampus are sustained by factors whose identities have remained…
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Concussion and Alzheimer’s disease link
New research has found concussions accelerate Alzheimer’s disease-related brain atrophy and cognitive decline in people who are at genetic risk for the condition. The findings, which appear in the journal Brain, show promise for detecting the influence…
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Early detection of Alzheimer’s disease using tau protein biomarker in platelets
Researchers have pioneered the technology that detects pathological oligomeric forms of brain tau protein levels in platelets to diagnose Alzheimer’s disease (AD) and other neurodegenerative disorders. More importantly, the ratio between this anomalous tau and the normal…
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Biomarker Autotaxin, related to diabetes predicts Alzheimer’s disease outcome
An enzyme found in the fluid around the brain and spine is giving researchers a snapshot of what happens inside the minds of Alzheimer’s patients and how that relates to cognitive decline. Iowa State University researchers say…
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Research shows Statins lower the risk of Alzheimer’s disease
The new study shows that, based on a sample of 399,979 Medicare beneficiaries, men and women who took statins two years or more lowered their risk of Alzheimer’s disease in the period spanning from 2009 to 2013. The…
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Combating Aging by removing damaged mitochondrial DNA
Researchers from UCLA and Caltech have made discoveries that might help slow and potentially reverse the process of aging in cells. They generated new methods that allow identification of factors that selectively remove damaged mitochondrial DNA, which…
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Fluselenamyl in conjuction with positron emission tomography (PET) scans shown effective in diagnosing early Alzheimer’s disease pathology
Researchers at Washington University School of Medicine in St. Louis have developed a chemical compound, named Fluselenamyl, that detects amyloid clumps better than current FDA-approved compounds. If a radioactive atom is incorporated into the compound, its location…
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Study reveals potential new treatment target Nuak1 kinase to prevent accumulation of protein in early Alzheimer’s disease
Taking a pill that prevents the accumulation of toxic molecules in the brain might someday help prevent or delay Alzheimer’s disease, according to scientists at Baylor College of Medicine, Texas Children’s Hospital and Johns Hopkins University School…
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