Basic-Science-Research
Basic-Science-Research
Latest Posts
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Research finds role of Messenger RNA in Huntington’s disease patholgy
A research effort at the Centre for Genomic Regulation in Barcelona, Spain, reveals new molecular mechanisms of Huntington’s disease. The results, published in The Journal of Clinical Investigation, question the approaches used up to now for treatment…
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Research finds that disruption of mitochondria-associated membrane in neurons as a possible pathological basis for Amyotrophic lateral sclerosis
A schematic illustration for MAM disruption in ALS. IP3R3, a MAM specific Ca2+ channel (an orange arrow, left), was mislocalized from the MAM in the ALS model mice (white arrow heads, right). Credit: Koji Yamanaka laboratory Amyotrophic…
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New method to study RNA G-quadruplexes to understand their role in cancer
An international research team led by the University of Leicester has made a breakthrough advance in understanding about RNA that could pave a new route for the development of anti-cancer drugs. This research is published in Nature…
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Synthetic binding protein called "NS1 Monobody" found to inhibit common cancer causing (RAS) mutation
Monobody NS1 binds to H-RAS or K-RAS protein and blocksRAS function by disrupting the protein’s ability to form active molecular pairs. Credit: John P. O’Bryan, et al. Researchers at the University of Illinois at Chicago have identified a new…
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Synthetic binding protein called “NS1 Monobody” found to inhibit common cancer causing (RAS) mutation
Monobody NS1 binds to H-RAS or K-RAS protein and blocksRAS function by disrupting the protein’s ability to form active molecular pairs. Credit: John P. O’Bryan, et al. Researchers at the University of Illinois at Chicago have identified a new…
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Researchers map short RNA molecules in single cell
Researchers at Karolinska Institutet have measured the absolute numbers of short, non-coding, RNA sequences in individual embryonic stem cells. The new method could improve the understanding of how our genes are regulated and different cell types develop.…
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