Tag: Bioinformatics
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A new algorithm to solve memory problems in large-scale human brain simulations
Researchers have come closer towards advancing technology to create computer simulations of the brain networks using exascale-class supercomputers. Their findings are published in journal Frontiers in Neuroinformatics. Credit: Forschungszentrum Jülich The human brain is a complex network composed of approximately 100 billion neurons. With current computing power, it is impossible to simulate 100 percent working brain.…
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Computational study finds new genetic targets for autism
Researchers at the University of Missouri created a new computational method that has connected several target genes to autism. Recent discoveries could lead to screening tools for young children and could help doctors determine correct interventions when diagnosing autism. Unlocking the genetic causes of autism requires data-intensive computations. In 2014, the National Science Foundation (NSF)…
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Finding new uses for old medication using computer program DrugPredict
Researchers at Case Western Reserve University School of Medicine have developed a computer program called DrugPredict to discover new indications for old drugs. This program matches existing data about FDA-approved drugs to diseases, and predicts potential drug efficacy. In a recent study published in Oncogene, the researchers successfully translated DrugPredict results into the laboratory, and…
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ResistoMap developed to track world wide microbial drug resistance
Scientists from the Federal Research and Clinical Center of Physical-Chemical Medicine, the Moscow Institute of Physics and Technology, and Data Laboratory have created the ResistoMap, an interactive visualization of gut resistome. Gut resistome is human gut microbiota potential to resist antibiotics and includes the set of all antibiotic resistance genes in the genomes of human…
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Zika virus lineage and evolution
The Zika virus remains a mystery. Isolated from macaque monkeys in the Ziika Forest in Uganda in 1947, the virus was shown to infect humans not long after, but it was identified as a benign disease, with mild symptoms. For this reason, it was not heavily studied until almost 70 years later when it appeared…
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Novel bio-signal measuring electrodes to advance health diagnosis using internet of things devices
Daegu Gyeongbuk Institute of Science and Technology (DGIST) announced that Professor Kyung-in Jang’s research team from the Department of Robotics Engineering succeeded in developing bio-signal measuring electrodes that can be mounted on Internet of Things (IoT) devices through joint research with a research team led by professor John Rogers of the University of Illinois, USA.…
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Computer based model InFlo predicts cell signals and network activity
A multi-institution academic-industrial partnership of researchers led by Case Western Reserve University School of Medicine has developed a new method to broadly assess cell communication networks and identify disease-specific network anomalies. The computer-based method, called InFlo, was developed in collaboration with researchers at Philips and Princeton University and predicts how cells send signals across networks…
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fABMACS – a new computational tool to simulate drug protein interaction
A new computational tool called fABMACS is helping scientists see beyond static images of proteins to more efficiently understand how these molecules function, which could ultimately speed up the drug discovery process. Simulation of BRD4 interacting with a potent inhibitor. Credit: Dr. Bradley Dickson, Rothbart Laboratory Van Andel Research Institute “The goal of targeted drug…
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