Calorie restricted diet promotes intestinal regeneration after injury

Dramatic calorie restriction have long been known to boost healthy lifespan and reduce the risk of heart attack, diabetes and other age-related conditions. In animal studies it is shown to extend life span in most animal species examined. Further research has shown that animals fed restricted-calorie diets are also better able to regenerate numerous tissues… Continue reading Calorie restricted diet promotes intestinal regeneration after injury

Local chemotherapy delivered directly to the brain preserves immune system for further immunotherapy in mouse models of glioblastoma multiforme

In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment.┬áThe researchers say their study results, reported… Continue reading Local chemotherapy delivered directly to the brain preserves immune system for further immunotherapy in mouse models of glioblastoma multiforme

Gut bacteria boost chemotherapy drugs in a research trial

Two bacterial species that inhabit the human gut activate immune cells to boost the effectiveness of a commonly prescribed anticancer drug, researchers report in Immunity.The study identifies a new role for Enterococcus hirae and Barnesiella intestinihominis in activating cancer-fighting T cell immune responses, thereby enhancing the effects of the chemotherapy drug cyclophosphamide. “The anti-cancer drug’s… Continue reading Gut bacteria boost chemotherapy drugs in a research trial