Metformin influences gut microbiome

A recent study at Sahlgrenska Academy and University of Girona indicates thatcontrol of blood glucose by metformin is achieved partly through modulation of the gut microbiota. Results of the study are published in journal Nature Medicine. Fredrik Bäckhed’s research group at Sahlgrenska Academy has previously shown that the gut microbiota is altered in patients with… Continue reading Metformin influences gut microbiome

ResistoMap developed to track world wide microbial drug resistance

Scientists from the Federal Research and Clinical Center of Physical-Chemical Medicine, the Moscow Institute of Physics and Technology, and Data Laboratory have created the ResistoMap, an interactive visualization of gut resistome. Gut resistome is human gut microbiota potential to resist antibiotics and includes the set of all antibiotic resistance genes in the genomes of human… Continue reading ResistoMap developed to track world wide microbial drug resistance

Role of diet and gut microbiome in the major depressive disorder

An international group of researchers headed by André Carvalho has published in Psychotherapy and Psychosomatic a paper that provides new data and prospects for the links between the intestinal flora and several disorders, notably depression. Persistent low-grade immune-inflammatory processes, oxidative and nitrosative stress and hypothalamic-pituitary-adrenal axis activation are integral to the pathophysiology of the major… Continue reading Role of diet and gut microbiome in the major depressive disorder

Sleep loss and change in gut microbiota

Results from a new clinical study conducted at Uppsala University suggest that curtailing sleep alters the abundance of bacterial gut species that have previously been linked to compromised human metabolic health. The new article is published in the journal Molecular Metabolism. Changes in the composition and diversity of the gut microbiota have been associated with… Continue reading Sleep loss and change in gut microbiota

Gut bacteria boost chemotherapy drugs in a research trial

Two bacterial species that inhabit the human gut activate immune cells to boost the effectiveness of a commonly prescribed anticancer drug, researchers report in Immunity.The study identifies a new role for Enterococcus hirae and Barnesiella intestinihominis in activating cancer-fighting T cell immune responses, thereby enhancing the effects of the chemotherapy drug cyclophosphamide. “The anti-cancer drug’s… Continue reading Gut bacteria boost chemotherapy drugs in a research trial