Tag: heart
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Understanding interaction between heart muscle cells and nanoscaffoding
Researchers from Moscow Institute of Physics and Technology (MIPT) have researched nanofibrous scaffold structure and its interaction with rat heart muscle cells. This study revealed that cardiac muscle cells envelop nanofibers as they grow, but fibroblasts tend to spread out on fibers forming several focal adhesion sites. Nanofibers enveloped by Heart muscle cells. The 3-D…
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I-Wire, a new Heart-on-a-Chip device to study biomechanical properties of heart
Scientists at Vanderbilt University have created a 3D organ-on-a-chip that can mimic the biomechanical properties of the heart. The device and the results of initial experiments are reported in the journal Acta Biomaterialia (for links see below). View of the cardiac fiber in the I-Wire device at two levels of magnification.Credit: VIIBRE Vanderbilt University The unique…
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Price tag for cardiovascular disease to reach 1 trillion dollars by 2035
A new study projects that by 2035, cardiovascular disease, the most costly and prevalent killer, if left unchecked, will place a crushing economic and health burden on the nation’s financial and health care systems. According to the study, in the next two decades, the number of Americans with cardiovascular disease will rise to 131.2 million…
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New generation robotic sleeve to support failing hearts
Every year about 2,100 people receives heart transplants in the United States, while 5.7 million suffer from heart failure. Given the scarcity of available donor hearts, clinicians and biomedical engineers from Boston Children’s Hospital and Harvard University have spent several years developing a mechanical alternative. Their proof of concept is reported in Science Translational Medicine:…
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Researchers study role of receptor endoglin in early development of heart and blood cells
New research from the University of Minnesota reveals endoglin as a critical factor in determining the fate of early undifferentiated cells during development. Endoglin, a receptor involved in cell signaling, has previously been known mostly for its function in blood vessels and angiogenesis. In a new paper published in the journal Nature Communications, researchers showed…