New targeted epigenetic therapy for lymphoma shows promise

New compounds targeting epigenetics have shown promise in treating patients with lymphoma, according to data presented at the Targeted Anticancer Therapies International Congress 2018 in Paris, France. ESMO’s phase-I oncology meeting featured early clinical studies with BET inhibitors and EZH2 inhibitors. Dr. Anastasios Stathis, head of the New Drugs Development Unit of the Oncology Institute… Continue reading New targeted epigenetic therapy for lymphoma shows promise

Novel and unique DNA vaccine to fight effectively against cancer antigen

Scientists at The Wistar Institute and Inovio pharmaceuticals, Inc. have devised a unique deoxyribonucleic acid (DNA) vaccine approach through molecular design to boost the immune responses induced against one of the most important cancer antigen targets. Research results were published in the journal Molecular Therapy. Cancer immunotherapy approaches, designed to harness the body’s natural immune… Continue reading Novel and unique DNA vaccine to fight effectively against cancer antigen

Piperlongumine, chemical from Indian pepper plant inhibits enzyme in cancer cells

UT Southwestern Medical Center scientists have uncovered the chemical process behind anti-cancer properties of a spicy Indian pepper plant called the long pepper, whose suspected medicinal properties date back thousands of years. The study is published in the Journal of Biological Chemistry. Dr. Westover’s lab used X-ray crystallography to create this molecular model of piperlongumine.Credit:… Continue reading Piperlongumine, chemical from Indian pepper plant inhibits enzyme in cancer cells

Understanding Leukemia cell movement gives clues to its resistance to treatment

This is a high-resolution render of unique environments in the bone marrow (blue, purple and green) as they are invaded and populated by leukemia cells (yellow).Credit: Edwin Hawkins and Delfim Duarte/Imperial College London New research is shedding light on how leukaemia cells can survive cancer treatment, suggesting new possibilities for stopping them in their tracks. Leukaemia has… Continue reading Understanding Leukemia cell movement gives clues to its resistance to treatment