Lymphatic filariasis, also known as elephantiasis, is a debilitating parasitic disease. It is caused primarily by three filarial worms: Wuchereria bancrofti, Brugia malayi, and Brugia timori. Infected mosquitoes transmit these parasites to humans. Once in the human body, the parasite larvae migrate to the lymphatic vessels. In the lymphatic system, they develop into adult worms, causing damage and obstruction to the lymphatic system. This blockage can lead to the accumulation of lymphatic fluid, leading to severe swelling and thickening of the skin, commonly affecting the legs, arms, and genitalia. This chronic condition often results in pain, severe disability, and social stigma. Lymphatic filariasis is a neglected tropical disease widespread in parts of Africa, Asia, the Pacific, and the Americas. Efforts to control and eliminate the disease primarily involve mass drug administration to interrupt transmission and measures aimed at reducing the mosquito vector populations.