Cortisol and Parkinson’s Disease

Research team from Daegu Gyeongbuk Institute Of Science And Technology (DGIST) has performed a high-throughput screening method to identify drug candidates that promote dopaminergic neuronal cell activation by inducing the expression of the parkin protein, the cell protection gene which can inhibit the death of dopaminergic neurons. The results of study are published in Scientific… Continue reading Cortisol and Parkinson’s Disease

Peripheral vision reaction time assessment to diagnose mild traumatic brain injury patients

A new test using peripheral vision reaction time could lead to earlier diagnosis and more effective treatment of mild traumatic brain injury, often referred to as a concussion, according to Peter J. Bergold, PhD, professor of physiology and pharmacology at SUNY Downstate Medical Center and corresponding author of a study published by the Journal of Neurotrauma. While… Continue reading Peripheral vision reaction time assessment to diagnose mild traumatic brain injury patients

New approach to Multiple Sclerosis treatment using immunosuppression and stem cells shows promise

New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person’s own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS). Five years after receiving the treatment, called high-dose immunosuppressive therapy and autologous hematopoietic cell transplant (HDIT/HCT), 69 percent of trial participants had survived without experiencing progression… Continue reading New approach to Multiple Sclerosis treatment using immunosuppression and stem cells shows promise

Research shows positive outcome for early epilepsy surgery

There are important, long-term gains from hastening the processes around surgical interventions against epilepsy, before the disease has had too much negative impact on brain functions and patients’ lives. These are some of the findings of a thesis for which more than 500 patients were studied and followed up. “Around one third of those undergoing… Continue reading Research shows positive outcome for early epilepsy surgery

Chronic headache and Vitamin D deficiency

Vitamin D deficiency may increase the risk of a chronic headache, according to a new study from the University of Eastern Finland. The findings were published in Scientific Reports. The Kuopio Ischaemic Heart Disease Risk Factor Study, KIHD, analyzed the serum vitamin D levels and occurrence of a headache in approximately 2,600 men aged between… Continue reading Chronic headache and Vitamin D deficiency

Deep brain magnetic stimulation provides precise and reliable activation of target neurons

Massachusetts General Hospital (MGH) researchers have developed what appears to be a significant improvement in the technology behind brain implants used to activate neural circuits responsible for vision, hearing or movement. The investigators, who are also affiliated with the Boston VA Healthcare System, describe their development of tiny magnetic coils capable of selectively activating target… Continue reading Deep brain magnetic stimulation provides precise and reliable activation of target neurons

MESO-BRAIN stem cell research project to develop 3D nanoprinting techniques to replicate neural networks

Aston University heading up major €3.3m stem cell research project to develop 3D nanoprinting techniques that could replicate brain’s neural networks. Aston University has launched MESO-BRAIN, a major stem cell research project which it hopes will develop three-dimensional (3D) nanoprinting techniques that can be used to replicate the brain’s neural networks. The cornerstone of the… Continue reading MESO-BRAIN stem cell research project to develop 3D nanoprinting techniques to replicate neural networks

Magnetoencephalography and computational analysis to accurately diagnose concussions

Simon Fraser University researchers have found that high-resolution brain scans, coupled with computational analysis, could play a critical role in helping to detect concussions that conventional scans might miss. In a study published in PLOS Computational Biology, Vasily Vakorin and Sam Doesburg show how magnetoencephalography (MEG), which maps interactions between regions of the brain, could… Continue reading Magnetoencephalography and computational analysis to accurately diagnose concussions

New biomarker based on expression of SHOX2 gene for predicting survival in Gliomas

Researchers at UT Southwestern Medical Center have found a new biomarker for glioma, a common type of brain cancer, that can help doctors determine how aggressive a cancer is and that could eventually help determine the best course of treatment. The findings are published in EBiomedicine. Researchers from the Harold C. Simmons Comprehensive Cancer Center found… Continue reading New biomarker based on expression of SHOX2 gene for predicting survival in Gliomas

NeuroVascular Unit on a chip created to mimic functions of Blood-brain barrier

The blood-brain barrier is a network of specialized cells that surrounds the arteries and veins within the brain. It forms a unique gateway that both provides brain cells with the nutrients they require and protects them from potentially harmful compounds. This is an illustration of the neurovascular unit on a chip.Credit: Dominic Doyle, Vanderbilt University An… Continue reading NeuroVascular Unit on a chip created to mimic functions of Blood-brain barrier