Tag: Neuroscience
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A new computational model to predict patient-specific growth of glioblastoma multiforme
Researchers at the University of Waterloo and the University of Toronto have developed a new computational model to predict the growth of glioblastoma multiforme (GBM) more accurately. The proliferation-invasion (PI) model is a mathematical model commonly used to describe the growth of glioblastoma multiforme (GBM). It relies on known values of two key parameters, the…
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Scientists identify neural pathways behind visual perceptual decision-making
Scientists at the National Eye Institute (NEI) have found that neurons in the superior colliculus are key players in allowing us to detect visual objects and events. This structure doesn’t help us recognize what the specific object or event is; instead, it’s the part of the brain that decides something is there at all. In…
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Potential treatment for Alzheimer’s dementia using cell therapy
Researchers from Gladstone Institute uncovered the therapeutic benefits of genetically improving interneurons with a voltage-gated sodium channel Nav1.1 and transplanting them into the brain of a mouse model of Alzheimer’s disease. This study is led by Jorge Palop, Ph.D., an assistant investigator at the Gladstone Institutes. The study findings are published in journal Neuron. Inhibitory…
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Researchers find possible link between autism and nuclear receptor protein LXRβ
Research by University of Houston scientists discovered a possible link between nuclear receptor protein LXRβ (Liver X receptor Beta) and autism spectrum disorder. They found that nuclear receptor LXRβ deletion causes poor development of dentate gyrus, a part of brain’s hippocampus. The dentate gyrus, or DG, is responsible for emotion and memory and is known…
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A new algorithm to solve memory problems in large-scale human brain simulations
Researchers have come closer towards advancing technology to create computer simulations of the brain networks using exascale-class supercomputers. Their findings are published in journal Frontiers in Neuroinformatics. Credit: Forschungszentrum Jülich The human brain is a complex network composed of approximately 100 billion neurons. With current computing power, it is impossible to simulate 100 percent working brain.…
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Effects of flu on brain
Group of researchers from Germany and USA studied effects of influenza virus on brain cells. The study published in the Journal of Neuroscience finds that female mice infected with two different strains of the flu shows changes in structure and function of the hippocampus. These changes persist for one month after infection. The long-term effect…
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Cortisol and Parkinson’s Disease
Research team from Daegu Gyeongbuk Institute Of Science And Technology (DGIST) has performed a high-throughput screening method to identify drug candidates that promote dopaminergic neuronal cell activation by inducing the expression of the parkin protein, the cell protection gene which can inhibit the death of dopaminergic neurons. The results of study are published in Scientific…
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Peripheral vision reaction time assessment to diagnose mild traumatic brain injury patients
A new test using peripheral vision reaction time could lead to earlier diagnosis and more effective treatment of mild traumatic brain injury, often referred to as a concussion, according to Peter J. Bergold, PhD, professor of physiology and pharmacology at SUNY Downstate Medical Center and corresponding author of a study published by the Journal of Neurotrauma. While…
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New approach to Multiple Sclerosis treatment using immunosuppression and stem cells shows promise
New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person’s own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS). Five years after receiving the treatment, called high-dose immunosuppressive therapy and autologous hematopoietic cell transplant (HDIT/HCT), 69 percent of trial participants had survived without experiencing progression…
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Research shows positive outcome for early epilepsy surgery
There are important, long-term gains from hastening the processes around surgical interventions against epilepsy, before the disease has had too much negative impact on brain functions and patients’ lives. These are some of the findings of a thesis for which more than 500 patients were studied and followed up. “Around one third of those undergoing…
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