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Ulcerative Colitis and Vitamin D levels
A new study led by researchers at Beth Israel Deaconess Medical Center has found that lower levels of vitamin D in the blood increase the risk of clinical relapse in patients with Ulcerative Colitis, an inflammatory bowel disease that causes long-lasting inflammation and ulcers in the colon. The study was published in the journal Clinical Gastroenterology…
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Role of diet and gut microbiome in the major depressive disorder
An international group of researchers headed by André Carvalho has published in Psychotherapy and Psychosomatic a paper that provides new data and prospects for the links between the intestinal flora and several disorders, notably depression. Persistent low-grade immune-inflammatory processes, oxidative and nitrosative stress and hypothalamic-pituitary-adrenal axis activation are integral to the pathophysiology of the major…
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Role of Vitamin D in acute respiratory infections
Vitamin D supplements protect against acute respiratory infections including colds and flu, according to a study led by the Queen Mary University of London. The study provides the most robust evidence yet that vitamin D has benefits beyond bone and muscle health, and could have major implications for public health policy, including the fortification of…
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Pollen pill treatment for Hay fever suppression
In a new study, published today in the journal JAMA, scientists from Imperial College London have found that a two-year course of pollen pill treatment is not enough to achieve lasting effects in hay fever (seasonal allergic rhinitis) patients, bolstering previous findings that more time is needed taking the medication to get lasting benefit.The study was…
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Gene therapy using lipid based nanoparticles
Lipid nanoparticles (SLNs and NLCs) are regarded as highly promising systems for delivering nucleic acids in gene therapy. Literature review by researchers at PharmaNanoGene describes these systems and their main advantages in gene therapy, such as their capacity to protect the gene material against degradation, to facilitate cell and nucleus internalization and to boost the transfection process. View…
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Price tag for cardiovascular disease to reach 1 trillion dollars by 2035
A new study projects that by 2035, cardiovascular disease, the most costly and prevalent killer, if left unchecked, will place a crushing economic and health burden on the nation’s financial and health care systems. According to the study, in the next two decades, the number of Americans with cardiovascular disease will rise to 131.2 million…
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New drug shows promise for COPD and other lung diseases
New research published online in The FASEB Journal reveals a potential drug to combat the life-threatening effects of chronic obstructive pulmonary disease (COPD). Specifically, the study investigated the efficacy of a receptor for advanced glycan end-products (RAGE)-specific antagonist chemical compound, FPS-ZM1, in mice, and found that this compound reverses the inflammatory response and has a…
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New approach to treating dementia using antisense oligonucleotides
In a study of mice and monkeys, NIH funded researchers showed that they could prevent and reverse some of the brain injury caused by the toxic form of a protein called tau. Scientists used a designer compound to prevent and reverse brain damage caused by tau in mice.Credit: Miller lab, Washington University, St. Louis, MO The results,…
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National Institutes of Health to expand ENCODE project
The National Institutes of Health plans to expand its Encyclopedia of DNA Elements (ENCODE) Project, a genomics resource used by many scientists to study human health and disease. Funded by the National Human Genome Research Institute (NHGRI), part of NIH, the ENCODE Project is generating a catalog of all the genes and regulatory elements the…
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