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New approach to Multiple Sclerosis treatment using immunosuppression and stem cells shows promise
New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person’s own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS). Five years after receiving the treatment, called high-dose immunosuppressive therapy and autologous hematopoietic cell transplant (HDIT/HCT), 69 percent of trial participants had survived without experiencing progression…
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Review of literature shows that Acupuncture improves medical treatment for depression and chronic pain
Health specialists at the University of York have found that acupuncture treatment can boost the effectiveness of standard medical care, lessening the severity of chronic pain and depression. In a report published in the National Institute for Health Research (NIHR) Journals Library, the researchers showed that there is significant evidence to demonstrate that acupuncture provides…
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Animal study shows combination of antibodies are effective in HIV
Without antiretroviral drug treatment, the majority of people infected with HIV ultimately develop AIDS, as the virus changes and evolves beyond the body’s ability to control it. But a small group of infected individuals called elite controllers possess immune systems capable of defeating the virus. They accomplish this by manufacturing broadly neutralizing antibodies, which can…
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Artificial intelligence project to identify skin cancer based on machine learning algorithm works as good as a doctor
Universal access to health care was on the minds of computer scientists at Stanford when they set out to create an artificially intelligent diagnosis algorithm for skin cancer. They made a database of nearly 130,000 skin disease images and trained their algorithm to visually diagnose potential cancer. From the very first test, it performed with…
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Research shows positive outcome for early epilepsy surgery
There are important, long-term gains from hastening the processes around surgical interventions against epilepsy, before the disease has had too much negative impact on brain functions and patients’ lives. These are some of the findings of a thesis for which more than 500 patients were studied and followed up. “Around one third of those undergoing…
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Large synthetic nanoparticles mimic biomolecules
Chemists at Carnegie Mellon University have demonstrated that synthetic nanoparticles can achieve the same level of structural complexity, hierarchy and accuracy as their natural counterparts biomolecules. The study, published in Science, also reveals the atomic-level mechanisms behind nanoparticle self-assembly. The structure of the largest gold nanoparticle to-date, Au246(SR)80, was resolved using x-ray crystallography. Credit: Rongchao…
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Analysis of interactome of Zika virus infected neural cells shows altered expression of more than 500 proteins
Zika virus (ZIKV) interferes with the cellular machinery controlling cell division and alters the expression of hundreds of genes responsible for guiding the formation and development of brain cells, according to findings of research published in Scientific Reports. Zika virus structure. Credit: Wikipedia / David Goodwill The association between Zika virus (ZIKV) infection and microcephaly has…
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New plant based compounds show promise for hepatitis B
Researchers have found that certain plant-derived products may help prevent and treat hepatitis B virus (HBV) infection. Proanthocyanidin (PAC) and its analogs, oolonghomobisflavanes, act by inhibiting viral entry into host cells. The life cycle of Hepatitis B Virus. Credit Dr. Graham Colm Wikipedia The investigators noted that PAC was effective even against treatment-resistant HBV strains,…
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Researcher discover role of protein CPEB4 in development of fatty liver
The scientists at IRB Barcelona discovered the role of a protein CPEB4 in the pathogenesis of nonalcoholic steatohepatitis (fatty liver). This condition generally leads to chronic inflammation, which can trigger fibrosis, cirrhosis and ultimately liver cancer. This study paves the way to examine therapeutic strategies to fight and prevent this disease. The results of the…

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