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Protein Wnt5a is important in sustaining adult neuron structure in mice hippocampus
Humans and other vertebrates depend on a portion of the brain called the hippocampus for learning, memory and their sense of location. Nerve cell structures in the adult hippocampus are sustained by factors whose identities have remained largely mysterious so far. Now, research led by a Johns Hopkins University biologist Dr. Kuruvilla sheds light on…
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Antidepressants use associated with birth defects
A new Université de Montréal study in the British Medical Journal reveals that antidepressants prescribed to pregnant women could increase the chance of having a baby with birth defects. The risk is 6 to 10 %, versus 3 to 5 % in women who do not take the drugs and it is high enough to…
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Collaboration between UCSF, Intel to develop deep learning analytics for healthcare
UC San Francisco’s Center for Digital Health Innovation (CDHI) today announced a collaboration with Intel Corporation to deploy and validate a deep learning analytics platform designed to improve care by helping clinicians make better treatment decisions, predict patient outcomes, and respond more nimbly in acute situations. The collaboration brings together Intel’s leading-edge computer science and…
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New generation robotic sleeve to support failing hearts
Every year about 2,100 people receives heart transplants in the United States, while 5.7 million suffer from heart failure. Given the scarcity of available donor hearts, clinicians and biomedical engineers from Boston Children’s Hospital and Harvard University have spent several years developing a mechanical alternative. Their proof of concept is reported in Science Translational Medicine:…
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Using focused magnetic stimulation of brain to improve precision memory
Northwestern Medicine scientists showed for the first time that non-invasive brain stimulation can be used like a scalpel, rather than like a hammer, to cause a specific improvement in precise memory. This is an individual receiving noninvasive brain stimulation (‘high-frequency, repetitive, transcranial electromagnetic stimulation’). Credit: Northwestern University Precise memory, rather than general memory, is critical…
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Malaria drug Chloroquine helps fight treatment resistant brain cancer
After her brain cancer became resistant to chemotherapy and then to targeted treatments, 26-year-old Lisa Rosendahl’s doctors gave her only a few months to live. Now a paper published in the journal eLife describes a new drug combination that has stabilized Rosendahl’s disease and increased both the quantity and quality of her life: Adding the…
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Research shows reduced Surgical Site Infections with use of Antimicrobial Sutures
New analyses of the published clinical studies indicate that antimicrobial sutures are effective for preventing surgical site infections (SSIs), and they can result in significant cost savings. The results are published in the British Journal of Surgery. In one analysis that included 21 randomized clinical trials, investigators found a risk of 138 surgical site infections…
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Multiple Sclerosis medication alemtuzumab can trigger severe B cell mediated brain inflammation
The multiple sclerosis (MS) therapy alemtuzumab can trigger severe, unpredictable side effects. This was the finding by a team led by Prof Dr Aiden Haghikia and Prof Dr Ralf Gold from the Department of Neurology of the Ruhr-Universität Bochum at St. Josef’s Hospital. In the journal Lancet Neurology, the scientists report on two patients for…
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Development of thin-film biomaterials using nanofibres to be used as scaffolding for bone regeneration
In future, it may be possible to use nanofibres to improve the attachment of bone implants, or the fibres may be used directly to scaffold bone regeneration. This would aid the healing of fractures and may enable the care of osteoporosis. This is detailed in a new dissertation. Hydroxyapatite nanofibre film produced at the University…
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