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Research uncovers link between long-term opioid use and preexisting psychiatric and behavioral disease
A wide range of pre-existing psychiatric and behavioral conditions and the use of psychoactive drugs could be important risk factors leading to long-term use of opioid pain medications, reports a study in Journal Pain, the official publication of the International Association for the Study of Pain (IASP). Using a nationwide insurance database, the researchers identified…
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Association between hearing loss and iron deficiency anemia
In a study published by JAMA Otolaryngology-Head & Neck Surgery, Kathleen M. Schieffer, B.S., of the Pennsylvania State University College of Medicine, and colleagues examined the association between sensorineural hearing loss and conductive hearing loss and iron deficiency anemia in adults ages 21 to 90 years in the United States. Hearing by Maklay62@pixelbay In 2014, approximately…
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Therapeutic benefits of synthetic cardiac stem cells
Researchers from North Carolina State University, the University of North Carolina at Chapel Hill and First Affiliated Hospital of Zhengzhou University have developed a synthetic version of a cardiac stem cell. These synthetic stem cells offer therapeutic benefits comparable to those from natural stem cells and could reduce some of the risks associated with stem…
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Early detection of Alzheimer’s disease using tau protein biomarker in platelets
Researchers have pioneered the technology that detects pathological oligomeric forms of brain tau protein levels in platelets to diagnose Alzheimer’s disease (AD) and other neurodegenerative disorders. More importantly, the ratio between this anomalous tau and the normal tau protein can discriminate Alzheimer’s disease patients from normal controls, and are associated with decreased cognitive impairment. This…
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Local chemotherapy delivered directly to the brain preserves immune system for further immunotherapy in mouse models of glioblastoma multiforme
In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment. The researchers say their study results, reported…
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Meditation helps fight major depressive disorder
A breathing-based meditation practice known as Sudarshan Kriya yoga helped alleviate severe depression in people who did not fully respond to antidepressant treatments, reports a study published in the Journal of Clinical Psychiatry from researchers in the Perelman School of Medicine at the University of Pennsylvania. The study bolsters the science behind the use of controlled…
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Increased risk of cardiovascular events in HIV patients
Current methods to predict the risk of heart attack and stroke vastly underestimate the risk in individuals with HIV, which is nearly double that of the general population, reports a new Northwestern Medicine study. “The actual risk of heart attack for people with HIV was roughly 50 percent higher than predicted by the risk calculator…
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Capsaicin, an active ingredient of chili peppers found to inhibit breast cancer cells in vitro
Capsaicin, an active ingredient of pungent substances such as chili or pepper, inhibits the growth of breast cancer cells. This was reported by a team headed by the Bochum-based scent researcher Prof. Dr. Dr. Dr. med. habil. Hanns Hatt and Dr. Lea Weber, following experiments in cultivated tumor cells. The study was published in the…
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Calcium channel blockers used for hypertension has potential to block cancer invasion
By screening already approved drugs, the team led by Postdoctoral Researcher Guillaume Jacquemet and Academy Professor Johanna Ivaska has discovered that calcium channel blockers can efficiently stop cancer cell invasion in vitro. Calcium channel blockers are currently used to treat hypertension, also known as high blood pressure, but their potential use in blocking cancer cell…
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