Many solid tumors are considered inoperable because they adhere to vital structures or the surgery would cause irreversible damages to the patients. In order to prevent the tumor growth or provide complete tumor resolution without surgery, chemotherapy and radiation are currently in clinical practice. Since these tumors are already locally advanced or have begun to… Continue reading University of Texas researchers developing radiotherapeutic gold nanoseeds to fight inoperable tumors
Many types of cancer become drug resistant, making them difficult to treat. Researchers with University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to selectively sensitize certain cancer cells to radiation therapy that may improve tumor control and reduce treatment-related side effects. In a paper published in Nature… Continue reading Research shows tumor-targeted radiosensitization using antibody drug conjugates may redues toxicity and improve outcome
Researchers from Boston University School of Medicine have discovered a possible strategy to treat colon cancers that are caused by the mutant KRAS gene, which is responsible for approximately half of all colon cancer cases. The findings, which appear online in the journal Molecular Cancer Research, may lead to better therapeutic agents to treat this… Continue reading Genetic targets in Colorectal Cancer: role of KRAS, MEK and TAK1 genes Identified.
The discovery, published online by Oncotarget journal, may lead to new therapies in managing patients with Colorectal Cancer (CRC). CRC is a complex disease caused by several genetic mutations and their consequences. In more than 80-percent of CRC patients, some of these mutations can lead to an increase in ?-catenin, a vital protein, leading to… Continue reading Research indicates role of protein c-Cbl in Colorectal Cancer
An independent panel convened by the National Institutes of Health has developed a 10-year roadmap for advancing research to prevent youth suicide. To help close research gaps related to youth suicide and to assess the scientific evidence, NIH convened the Pathways to Prevention Workshop on March 29-30, 2016. The report includes recommendations to address these… Continue reading NIH panel discuss roadmap for advancing research to prevent youth suicide.
Two bacterial species that inhabit the human gut activate immune cells to boost the effectiveness of a commonly prescribed anticancer drug, researchers report in Immunity.The study identifies a new role for Enterococcus hirae and Barnesiella intestinihominis in activating cancer-fighting T cell immune responses, thereby enhancing the effects of the chemotherapy drug cyclophosphamide. “The anti-cancer drug’s… Continue reading Gut bacteria boost chemotherapy drugs in a research trial
A team of Mayo Clinic researchers has, for the first time, successfully mapped patterns of prostate cancer recurrence, following surgery. Using C-11 choline PET imaging and multiparametric MRI, researchers found an anatomically diverse pattern of recurrence, which may help optimize treatment of patients whose prostate cancer returns after surgery. The research findings are published today… Continue reading Mapping recurrent prostate cancer using C-11 choline PET and multiprarmetric MRI
Thousands died and more than 13 million people fell ill with malaria caused by the parasite Plasmodium vivax last year. There is no vaccine for the disease, partly because multiple strains of P. vivax circulate globally, making it difficult to develop a vaccine. Now, researchers studying a protein crucial for the parasite’s survival have found… Continue reading New vaccine targets found for Plasmodium vivax Malaria
Girls with attention deficit hyperactivity disorder are at higher risk than girls without ADHD for multiple mental disorders that often lead to cascading problems such as abusive relationships, teenage pregnancies, poor grades and drug abuse, UCLA psychologists report in the journal Pediatrics. The researchers, who conducted by far the most comprehensive analysis of girls and… Continue reading Research shows girls with ADHD are at higher risk for other mental health issues.
Professor Peter O’Connor and Dr Maria van Agthoven in the Department of Chemistry have invented a device which makes 2D mass spectrometry – an effective process for analysing and sequencing proteins. This could enable researchers and companies to produce data-driven results on how protein molecules function, more easily and cheaply. 2D mass spectrometry allows chemists… Continue reading Researchers in University of Warwickshire develop 2D mass spectrometry using Linear ion trap.