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Research finds link between Vitamin D and Aging and Longevity
Research at the Buck Institute shows that vitamin D works through genes known to influence longevity and impacts processes associated with many human age-related diseases. The study, published in Cell Reports, may explain why vitamin D deficiency has been linked to breast, colon and prostate cancer, as well as obesity, heart disease and depression. “Vitamin…
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Understanding pathology behind triple negative breast cancer
A study conducted at the Research Institute of the McGill University Health Centre (RI-MUHC) suggests screening breast cancer patients for the prolactin receptor could improve the prognosis for patient and may help them avoid unnecessary and invasive treatments. Using a database of 580 women with triple negative breast cancer (TNBC), the researchers found that survival…
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Scientists find why it is difficult to create vaccine for Hepatitis C virus
Researchers have been trying for decades to develop a vaccine against the globally endemic hepatitis C virus (HCV). Now scientists at The Scripps Research Institute (TSRI) have discovered one reason why success has so far been elusive. Using a sophisticated array of techniques for mapping tiny molecular structures, the TSRI scientists analyzed a lab-made version…
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Onionin A, natural compound from onions found effective against Epithelial Ovarian Cancer
Research from Kumamoto University, Japan has found that a natural compound isolated from onions, onionin A (ONA), has several anti-ovarian cancer properties. This discovery is a result of research on the effects of onionin A on a preclinical model of epithelial ovarian cancer (EOC) both in vivo and in vitro. This research comes from the…
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Researchers found new type of repair used by telomeres to form new DNA
(Philadelphia) – Maintaining the ends of chromosomes, called telomeres, allows cells to continuously divide and achieve immortality. In a new study published this week in Nature, senior author Greenberg and colleagues have developed a first-of-its- kind system to observe repair to broken DNA in newly synthesized telomeres, an effort which has implications for designing new cancer drugs.…
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Caloric restriction can be protective to brain
Studies of different animal species suggest a link between eating less and living longer, but the molecular mechanisms by which caloric restriction affords protection against disease and extends longevity are not well understood. New clues to help solve the mystery are presented in an article published in the September issue of Aging Cell by scientists…
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New approach to targeted fluorescent imaging in cancer diagnosis provides improved results
Tumor detection using targeted fluorescent imaging probes is a promising technology that takes advantage of specific molecular events occurring in cancer tissues. However, currently available probes that use this technology fail to maximize their specificity for tumors because of strong off-target signals, and thus, have limited ability to detect small tumors in a short timespan…
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Research links collagen structural changes to worse prognosis in pancreatic cancer
(Madison) University of Wisconsin-Madison researchers found first evidence linking a disturbance of the most common protein in the body with a poor outcome in pancreatic cancer. Results of the study are published in the journal Oncotarget. The study reinforces growing evidence that collagen, which forms fibrous networks in skin, tendons and muscles, is intimately involved in…
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Research shows link between impaired glucose tolerance and adverse cardiac structure and function.
A study of U.S. Hispanics with diabetes mellitus showed a link between impaired glucose regulation and adverse measures of cardiac function and structure. Researchers at Columbia University’s Mailman School of Public Health in collaboration with colleagues from Wake Forest Medical School and six other institutions extended previous knowledge regarding the concept of ‘diabetic cardiomyopathy, by…
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