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National Institute of Health scientists find genes causing frustrating syndrome
Scientists at the National Institutes of Health have identified a genetic explanation for a syndrome characterized by multiple frustrating and difficult-to-treat symptoms, including dizziness and lightheadedness, skin flushing and itching, gastrointestinal complaints, chronic pain, and bone and joint problems. Some people who experience these diverse symptoms have elevated levels of tryptase — a protein in…
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Unvaccinated individuals cost more than 7 billion dollars a year in United States
Vaccine-preventable diseases among adults cost the U.S. economy $8.95 billion in 2015, and unvaccinated individuals are responsible for 80 percent, or $7.1 billion, of the tab, according to the most comprehensive analysis to date from the University of North Carolina at Chapel Hill. Researchers at the UNC Eshelman School of Pharmacy, led by Associate Professor…
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Understanding cause of memory loss in Tauopathies
Tauopathies are a group of neurodegenerative disorders, including Alzheimer’s disease that are characterized by the deposition of aggregates of the tau protein inside brain cells. A new study reveals that the cutting of tau by an enzyme called caspase-2 may play a critical role in the disordered brain circuit function that occurs in these diseases.…
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Vitamins A and Vitamin C help erase epigenetic memory held by cells
Vitamins A and C aren’t just good for your health, they affect your DNA too. Researchers at the Babraham Institute and their international collaborators have discovered how vitamins A and C act to modify the epigenetic ‘memory’ held by cells; insight which is significant for regenerative medicine and our ability to reprogramme cells from one…
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Zika virus evolution and spread
In a study published in Pathogens and Global Health, researchers have modelled the evolutionary development and diversity of the Zika virus to better understand how infection spreads between populations and how the virus reacts with the immune system. Such an understanding is essential if an effective vaccine is to be developed. First found in Uganda…
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Experimental medication using encapsulated cell therapy for treating Glaucoma
An experimental drug, consisting of cells manufactured and implanted in the eye to stimulate optic nerve growth and activity, could be an entirely new way of fighting glaucoma, according to BrightFocus Foundation. BrightFocus is helping fund a recently launched, Phase 2 [or mid-level] clinical trial designed to test the new treatment. The trial will be…
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New molecule Beta-LGND2 may help fight obesity
New research, published online in The FASEB Journal, suggests that activation of a chemical called Beta-LGND2 by the estrogen receptor Beta (ER-Beta) reduces obesity and metabolic diseases in mice by converting bad fat (white fat) to good fat (brown fat). This is significant as brown fat increases metabolism and may facilitate weight loss. “Although there…
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Mining Twitter database for cardiovascular disease research
(PHILADELPHIA) For years, marketers and other commercial data-miners have been using Twitter’s vast database of “tweets” to gauge consumer attitudes and track events. Now medical researchers are getting in on the trend. Researchers from the Perelman School of Medicine at the University of Pennsylvania completed a pilot analysis of archived tweets on cardiovascular disease. In…
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Propranolol’s role as a cancer drug
Propranolol, a beta-blocker commonly prescribed to treat irregular heart rates and other conditions, has significant anti-cancer properties, say researchers in a new clinical study published in ecancermedicalscience. The Repurposing Drugs in Oncology (ReDO) project, an international collaboration between the Anticancer Fund, Belgium, and US based GlobalCures, says that existing and widely-used non-cancer drugs may represent…
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