Tag: Autism-gene
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Researchers find possible link between autism and nuclear receptor protein LXRβ
Research by University of Houston scientists discovered a possible link between nuclear receptor protein LXRβ (Liver X receptor Beta) and autism spectrum disorder. They found that nuclear receptor LXRβ deletion causes poor development of dentate gyrus, a part of brain’s hippocampus. The dentate gyrus, or DG, is responsible for emotion and memory and is known…
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Computational study finds new genetic targets for autism
Researchers at the University of Missouri created a new computational method that has connected several target genes to autism. Recent discoveries could lead to screening tools for young children and could help doctors determine correct interventions when diagnosing autism. Unlocking the genetic causes of autism requires data-intensive computations. In 2014, the National Science Foundation (NSF)…
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Researchers identify biomarker for autism caused by Dup15q syndrome
Researchers at the UCLA Center for Autism Research and Treatment have identified a signature brain-wave pattern for children with autism spectrum disorder related to a genetic condition known as Dup15q syndrome. The research team noted that this signature is among the first quantitative biomarkers identified in electroencephalogram tests discovered for any syndrome highly associated with…
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Similar epigenetic mark found in brain cells of different types of autism disorder
UCLA scientists and their colleagues have found evidence that an abnormal pattern of brain cells is common in people with different types of autism disorders. The abnormal pattern discovered in the study, reported in journal Cell, concerns a certain type of “epigenetic mark,” a chemical modification that occurs frequently on chromosomes and helps regulate the…
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Similar brain molecular signatures found in people with autism spectrum disorder
Autism spectrum disorder is caused by a variety of factors, both genetic and environmental. But a new study led by UCLA scientists provides further evidence that the brains of people with the disorder tend to have the same “signature” of abnormalities at the molecular level. The scientists analyzed 251 brain tissue samples from nearly 100…
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Research shows genetic link between autism spectrum disorder and mitochondrial DNA (mtDNA)
Cornell University researchers have confirmed a genetic link between mitochondrial DNA (mtDNA), which is passed on from the mother, and some forms of autism spectrum disorder (ASD). Previous research suggested a link between mitochondrial functional defects and autism spectrum disorder, but those studies included small sample sizes and could not verify whether the cause was…
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Scientists link single gene mutation of NF1 to some cases of autism spectrum disorder
Scientists have linked mutations in a single gene to autism in people who have a rare tumor syndrome typically diagnosed in childhood. The findings, in patients with neurofibromatosis type 1 (NF1), may lead to a better understanding of the genetic roots of autism in the wider population. The findings are published Oct. 19 in the…
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Researchers found unique genetic basis in autism genes that may lead to earlier diagnosis
Ben-Gurion University of the Negev (BGU) researchers are a step closer to understanding the genetic basis of autism, which they hope will lead to earlier diagnosis of what is rapidly becoming the most prevalent developmental disorder worldwide. In the study published in Behavior Genetics, the researchers examined the sequences of more than 650 genes associated…
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New Mouse Model used find potential drug target for Autism
(Philadelphia) A study of a new mouse model identifies a drug target that has the potential to increase social interaction in individuals with some forms of autism spectrum disorder (ASD), according to researchers in the Perelman School of Medicine at the University of Pennsylvania. The team published their work in Biological Psychiatry. Although medications are…
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