New approach to targeted fluorescent imaging in cancer diagnosis provides improved results

Tumor detection using targeted fluorescent imaging probes is a promising technology that takes advantage of specific molecular events occurring in cancer tissues. However, currently available probes that use this technology fail to maximize their specificity for tumors because of strong off-target signals, and thus, have limited ability to detect small tumors in a short timespan… Continue reading New approach to targeted fluorescent imaging in cancer diagnosis provides improved results

Novel cancer therapy developed at University of Oklahoma based on photothermal therapy using carbon nanotubes

University of Oklahoma researchers have collaborated to design a novel, non-invasive cancer therapy that could eliminate tumors without affecting the healthy cells in the body. The cancer therapy targets specific cancer cells using single-walled carbon nanotubes that bind directly to the tumor, then are heated with near-infrared light. The OU photothermal therapy is most effective… Continue reading Novel cancer therapy developed at University of Oklahoma based on photothermal therapy using carbon nanotubes

University of Iowa’s hybridoma bank, a national treasure

The Developmental Studies Hybridoma Bank at the UI was created by the National Institutes of Health in 1986 to store and distribute laboratory-produced proteins used for cancer research and other scientific pursuits. University of Iowa biology professor David Soll has run the bank for the past 20 years as an independent nonprofit entity, creating, storing,… Continue reading University of Iowa’s hybridoma bank, a national treasure

Glioblastoma’s dependence of cholesterol from astrocytes, a possible new therapeutic target

Researchers at University of California San Diego School of Medicine, Ludwig Institute for Cancer Research and The Scripps Research Institute, with colleagues in Los Angeles and Japan, report that depriving deadly brain cancer cells of cholesterol, which they import from neighboring healthy cells, specifically kills tumor cells and caused tumor regression and prolonged survival in… Continue reading Glioblastoma’s dependence of cholesterol from astrocytes, a possible new therapeutic target

Scientists find how cancer cells metabolizes glucose, providing new therapeutic target

Cancer cells have their own unique way of reproducing, involving a shrewd metabolic reprograming that has been observed in virtually all types of cancer but not in normal cells. Now, University of Rochester Medical Center scientists have pinpointed one key source of the problem, which could lead to new treatment opportunities. In an article published… Continue reading Scientists find how cancer cells metabolizes glucose, providing new therapeutic target

Researchers use machine learning to identify different cancer cell types

National Institutes of Health, COBRE Center for Cancer Research Development at Rhode Island Hospital, Rhode Island Foundation Medical Research Grant, Jason and Donna McGraw Weiss Brown University researchers have developed a new image analysis technique to distinguish two key cancer cell types associated with tumor progression. The approach could help in pre-clinical screening of cancer… Continue reading Researchers use machine learning to identify different cancer cell types

Controlling amyloid formation in cancer cells a possible target for drug discovery and development.

A study published by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine describes that certain proteins playing a role in cancer progression and metastasis are stored as amyloid bodies in dormant cancer cells. Once the amyloid bodies disaggregate, the cancer cells become active again. The findings were published in… Continue reading Controlling amyloid formation in cancer cells a possible target for drug discovery and development.

New Imaging technique to detect Chromatin in the cell (Partial Wave Spectroscopic Microscopy)

When scientists finished decoding the human genome in 2003, they thought the findings would help us better understand diseases, discover genetic mutations linked to cancer, and lead to the design of smarter medicine. Now it’s 13 years later, and not all of these ideas have not yet come to fruition. It turns out that genes… Continue reading New Imaging technique to detect Chromatin in the cell (Partial Wave Spectroscopic Microscopy)