Tag: Biomarkers
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New retinal biomarker for identifying early Alzheimer’s disease
Researchers at the Complutense University of Madrid (UCM) have identified changes in retinal layer thickness, inflammation or thinning in patients with mild Alzheimer’s disease. These changes are identified with non invasive assessment using optical coherence tomography may be an important biomarker for early diagnosis. Researchers observed that in some patients diagnosed with Alzheimer’s disease, the…
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New biomarkers to predict the success of diabetic macular edema treatment
Researchers have found new biomarkers that predict prognosis following current treatments for diabetic macular edema. The research was led by Dr. Rajeev Muni, a vitreoretinal surgeon at St. Michael’s Hospital. The study is published in the journal JAMA Ophthalmology. Diabetic macular edema is one the common complication of Diabetes. It is associated with the accumulation of fluid in the…
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New biomarkers for assessing Alzheimers dementia risk and early diagnosis
Researchers from the University of Texas have analyzed biomarkers to predict future risk of dementia. Their findings are published in journal Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. Dementia is a rising tidal wave of devastation for families and society. Age is the biggest risk factor. Alzheimer’s disease, which is the leading cause…
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Developing new biomarkers for liver cancer with RNA splicing techniques
Researchers at Cold Spring Harbor Laboratory (CSHL), led by Professor Adrian Krainer, have developed a method for identifying splicing-based biomarkers for hepatocellular carcinoma (HCC). They have published their findings in journal Genome Research. Different versions, or isoforms, of messenger RNAs generated by the human AFMID gene, are represented, showing their relative prevalence in cancerous (top)…
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New target receptor for treating depression GPR158
Researchers from the Scripps Research Institute find a new target receptor called GPR158 for treating depression. Their research shows that individuals with high levels of above receptor may be more susceptible to depression following chronic stress. “The next step in this process is to come up with a drug that can target this receptor,” says Kirill…
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New biomarkers proposed for earlier diagnosis of autism
Researchers at the University of Warwick have developed new blood and urine tests to indicate those with autism. The biomarkers in blood and urine could lead to earlier detection of autism spectrum disorders (ASD) and consequently children with autism could be given appropriate treatment much earlier in their lives. The findings are published in Molecular…
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New imaging based biomarker to predict success of atrial fibrillation treatment
Researchers report successful use of biomarker based on heart imaging to predict the usefulness of catheter ablation to treat atrial fibrillation (Afib). Researchers analyzed the level of dys-synchrony in the left atrium as useful biomarker for success of the catheter ablation. The study is published in the Journal of the American College of Cardiology: Cardiovascular…
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Researchers identify biomarker for autism caused by Dup15q syndrome
Researchers at the UCLA Center for Autism Research and Treatment have identified a signature brain-wave pattern for children with autism spectrum disorder related to a genetic condition known as Dup15q syndrome. The research team noted that this signature is among the first quantitative biomarkers identified in electroencephalogram tests discovered for any syndrome highly associated with…
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Using ribosomal protein expression patterns as cancer biomarker
A research team at the University of Basel’s Biozentrum has investigated the expression of ribosomal proteins in a wide range of human tissues including tumors and discovered a cancer type specific signature. The study is reported in journal Genome Biology. Researchers think that these signature could be used for predicting progression and survival. Gene expression level of individual…
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Tau protein as biomarker for predicting recovery time after concussion
Elevated levels of the brain protein tau following a sport-related concussion are associated with a longer recovery period and delayed return to play for athletes, according to a study published in Journal Neurology. The findings suggest that tau, which can be measured in the blood, may serve as a marker to help physicians determine an…
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