Biomarkers
Biomarkers, short for biological markers, are measurable indicators of some biological state or condition, and they play a critical role in both medical research and clinical practice. They are typically used to objectively measure and evaluate physiological processes, pathological states, or pharmacological responses to a therapeutic intervention. Biomarkers can be found in various bodily fluids or tissues and can take many forms, including genes, enzymes, hormones, and antibodies. Their utility spans a wide range of applications, such as diagnosing diseases, monitoring disease progression, predicting treatment response, and identifying individuals at risk for particular conditions. The development and validation of biomarkers are subject to rigorous scientific research, ensuring their reliability and effectiveness in clinical settings. Advances in technology and bioinformatics have greatly enhanced the discovery and utilization of biomarkers, making them increasingly integral to personalized medicine, where treatment and prevention strategies are tailored to individual patients based on their unique biomarker profiles.
Biomarkers
Latest Posts
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CCT5 and ELF1: Key Biomarkers for Predicting Neoadjuvant Chemoradiotherapy Response and Prognosis in Locally Advanced Rectal Cancer
Researchers identified CCT5 and ELF1 as significant biomarkers for determining treatment response and prognosis in locally advanced rectal cancer (LARC) patients undergoing neoadjuvant chemoradiotherapy (NCRT). Their study showed that high expression levels of these genes were associated…
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NPAS4 genetic biomarker for depression symptoms identified in an animal study
Scientists at the Medical University of South Carolina (MUSC) have identified a stress-regulated gene that is responsible for the link between long-term stress and anhedonia, or the loss of interest in previously pleasurable activities, in an animal…
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New retinal biomarker for identifying early Alzheimer’s disease
Researchers at the Complutense University of Madrid (UCM) have identified changes in retinal layer thickness, inflammation or thinning in patients with mild Alzheimer’s disease. These changes are identified with non invasive assessment using optical coherence tomography may…
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New biomarkers to predict the success of diabetic macular edema treatment
Researchers have found new biomarkers that predict prognosis following current treatments for diabetic macular edema. The research was led by Dr. Rajeev Muni, a vitreoretinal surgeon at St. Michael’s Hospital. The study is published in the journal JAMA…
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New biomarkers for assessing Alzheimers dementia risk and early diagnosis
Researchers from the University of Texas have analyzed biomarkers to predict future risk of dementia. Their findings are published in journal Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. Dementia is a rising tidal wave of…
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Developing new biomarkers for liver cancer with RNA splicing techniques
Researchers at Cold Spring Harbor Laboratory (CSHL), led by Professor Adrian Krainer, have developed a method for identifying splicing-based biomarkers for hepatocellular carcinoma (HCC). They have published their findings in journal Genome Research. Different versions, or isoforms,…
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New target receptor for treating depression GPR158
Researchers from the Scripps Research Institute find a new target receptor called GPR158 for treating depression. Their research shows that individuals with high levels of above receptor may be more susceptible to depression following chronic stress. “The next…
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New biomarkers proposed for earlier diagnosis of autism
Researchers at the University of Warwick have developed new blood and urine tests to indicate those with autism. The biomarkers in blood and urine could lead to earlier detection of autism spectrum disorders (ASD) and consequently children…
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New imaging based biomarker to predict success of atrial fibrillation treatment
Researchers report successful use of biomarker based on heart imaging to predict the usefulness of catheter ablation to treat atrial fibrillation (Afib). Researchers analyzed the level of dys-synchrony in the left atrium as useful biomarker for success…
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Researchers identify biomarker for autism caused by Dup15q syndrome
Researchers at the UCLA Center for Autism Research and Treatment have identified a signature brain-wave pattern for children with autism spectrum disorder related to a genetic condition known as Dup15q syndrome. The research team noted that this…
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