Tag: Biomarkers
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Early detection of Alzheimer’s disease using tau protein biomarker in platelets
Researchers have pioneered the technology that detects pathological oligomeric forms of brain tau protein levels in platelets to diagnose Alzheimer’s disease (AD) and other neurodegenerative disorders. More importantly, the ratio between this anomalous tau and the normal tau protein can discriminate Alzheimer’s disease patients from normal controls, and are associated with decreased cognitive impairment. This…
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Biomarker Autotaxin, related to diabetes predicts Alzheimer’s disease outcome
An enzyme found in the fluid around the brain and spine is giving researchers a snapshot of what happens inside the minds of Alzheimer’s patients and how that relates to cognitive decline. Iowa State University researchers say higher levels of the enzyme, autotaxin, significantly predict memory impairment and Type 2 diabetes. Autotaxin often studied in…
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New lung cancer biomarker Protein PD-1 for predicting survival
The biomarker PD-1, a protein, could potentially be used to predict survival or disease-free survival of lung cancer patients who have had the tumor surgically removed. This is substantiated by the results of a study conducted under the direction of the Comprehensive Cancer Center (CCC) of MedUni Vienna and Vienna General Hospital, together with MedUni…
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Research categorizes depression in to 4 subtypes based on fMRI scans
Patients with depression can be categorized into four unique subtypes defined by distinct patterns of abnormal connectivity in the brain, according to new research from Weill Cornell Medicine. In a collaborative study published in Nature Medicine, Dr. Conor Liston, an assistant professor of neuroscience in the Feil Family Brain and Mind Institute and an assistant…
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New tool to discover bio-markers for aging using In-silico Pathway Activation Network Decomposition Analysis (iPANDA)
Today the Biogerontology Research Foundation announced the international collaboration on signaling pathway perturbation-based transcriptomic biomarkers of aging. On November 16th scientists at the Biogerontology Research Foundation alongside collaborators from Insilico Medicine, Inc, the Johns Hopkins University, Albert Einstein College of Medicine, Boston University, Novartis, Nestle and BioTime Inc. announced the publication of their proof of…
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Research links collagen structural changes to worse prognosis in pancreatic cancer
(Madison) University of Wisconsin-Madison researchers found first evidence linking a disturbance of the most common protein in the body with a poor outcome in pancreatic cancer. Results of the study are published in the journal Oncotarget. The study reinforces growing evidence that collagen, which forms fibrous networks in skin, tendons and muscles, is intimately involved in…
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Universal biomarker to detect aging cell
(Manchester, UK) Scientists have discovered a new way to look for ageing cells across a wide range of biological materials; the new method will boost understanding of cellular development and ageing as well as the causes of diverse diseases. Cellular senescence is a fundamental biological process involved in every day embryonic and adult life, both…
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