Biomarkers
Biomarkers, short for biological markers, are measurable indicators of some biological state or condition, and they play a critical role in both medical research and clinical practice. They are typically used to objectively measure and evaluate physiological processes, pathological states, or pharmacological responses to a therapeutic intervention. Biomarkers can be found in various bodily fluids or tissues and can take many forms, including genes, enzymes, hormones, and antibodies. Their utility spans a wide range of applications, such as diagnosing diseases, monitoring disease progression, predicting treatment response, and identifying individuals at risk for particular conditions. The development and validation of biomarkers are subject to rigorous scientific research, ensuring their reliability and effectiveness in clinical settings. Advances in technology and bioinformatics have greatly enhanced the discovery and utilization of biomarkers, making them increasingly integral to personalized medicine, where treatment and prevention strategies are tailored to individual patients based on their unique biomarker profiles.
Biomarkers
Latest Posts
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Using ribosomal protein expression patterns as cancer biomarker
A research team at the University of Basel’s Biozentrum has investigated the expression of ribosomal proteins in a wide range of human tissues including tumors and discovered a cancer type specific signature. The study is reported in journal Genome Biology.…
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Tau protein as biomarker for predicting recovery time after concussion
Elevated levels of the brain protein tau following a sport-related concussion are associated with a longer recovery period and delayed return to play for athletes, according to a study published in Journal Neurology. The findings suggest that…
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Early detection of Alzheimer’s disease using tau protein biomarker in platelets
Researchers have pioneered the technology that detects pathological oligomeric forms of brain tau protein levels in platelets to diagnose Alzheimer’s disease (AD) and other neurodegenerative disorders. More importantly, the ratio between this anomalous tau and the normal…
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Biomarker Autotaxin, related to diabetes predicts Alzheimer’s disease outcome
An enzyme found in the fluid around the brain and spine is giving researchers a snapshot of what happens inside the minds of Alzheimer’s patients and how that relates to cognitive decline. Iowa State University researchers say…
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New lung cancer biomarker Protein PD-1 for predicting survival
The biomarker PD-1, a protein, could potentially be used to predict survival or disease-free survival of lung cancer patients who have had the tumor surgically removed. This is substantiated by the results of a study conducted under…
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Research categorizes depression in to 4 subtypes based on fMRI scans
Patients with depression can be categorized into four unique subtypes defined by distinct patterns of abnormal connectivity in the brain, according to new research from Weill Cornell Medicine. In a collaborative study published in Nature Medicine, Dr.…
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New tool to discover bio-markers for aging using In-silico Pathway Activation Network Decomposition Analysis (iPANDA)
Today the Biogerontology Research Foundation announced the international collaboration on signaling pathway perturbation-based transcriptomic biomarkers of aging. On November 16th scientists at the Biogerontology Research Foundation alongside collaborators from Insilico Medicine, Inc, the Johns Hopkins University, Albert…
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Research links collagen structural changes to worse prognosis in pancreatic cancer
(Madison) University of Wisconsin-Madison researchers found first evidence linking a disturbance of the most common protein in the body with a poor outcome in pancreatic cancer. Results of the study are published in the journal Oncotarget. The study…
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Universal Biomarker Assay To Detect Aging Cell
Scientists have developed a new, more effective method for detecting aging cells across various biological materials, promising to enhance our understanding of cellular development, aging, and disease causation. This innovative technique, detailed as a robust, universal biomarker…
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