Category: Microbiology
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New strategy to reduce antibiotic resistance using an extracellular polymeric substance inhibitor
Researchers from KU Leuven in Belgium have developed a new antibacterial strategy that weakens bacteria by preventing them from cooperating. The researchers showed that blocking slime (extracellular polymeric substance) production of salmonella bacteria weakens the bacterial community, making it easier to remove. They used a chemical, antibacterial substance 2-cyclopentenyl-5-(4-chlorophenyl)-2-aminoimidazole, a specific member of the class…
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Web application to help discover new antibiotics to fight gram negative bacteria
A new web app eNTRyway speeds the discovery of drugs to kill Gram-negative bacteria by quickly evaluating potential drugs ability to accumulate in these bacterial cell. Entryway calculates physiochemical properties of molecules and compares to a training set of compounds. The tool also offers insights into discrete chemical changes that can convert drugs that kill…
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Bacteriophage treatment for alcohol related liver disease
Researchers from King’s College London and the University of California San Diego School of Medicine conducted an animal study in mice and shown promise of bacteriophage therapy in treating alcohol-related liver disease. This research is published in journal Nature. The team discovered that patients with severe alcoholic hepatitis had high numbers of a destructive gut…
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Researchers develop self sterilizing bacterial air filter using graphene
Rice University researchers have developed self-sterilizing bacterial air filters using graphene. Workings of this novel air filter are published in the American Chemical Society journal ACS Nano. This devise captures bacteria, fungi, spores, prions, endotoxins and other biological contaminants carried by droplets, aerosols and particulate matter. The filter then prevents the microbes and other contaminants…