Medical News Observer

Human Lung Alveolus Chip To Study Radiation Injury

A multi-disciplinary research team at the Wyss Institute for Biologically Inspired Engineering and Boston Children’s Hospital, led by Dr. Donald Ingber, has developed an Lung Alveolus Chip to closely mimic radiation-induced lung injury (RILI) and radiation dose sensitivity in the human lung. This Lung Alveolus Chip is a system created using human lung cells that…
Smart EEG Reading Brain Cap to Speed Up Stroke Diagnosis in Ambulances

Researchers from Amsterdam University Medical Centers developed a brain-wave cap to effectively diagnose large ischemic strokes in ambulances, enabling quicker and more accurate treatment. The cap conducts an EEG in the ambulance to determine the stroke type and size, which dictates the treatment – blood thinners for small strokes and mechanical clot removal in specialized…
PARMESAN – an automated tool to extract gene-gene and drug-gene relations from literature

Researchers develop PARsing ModifiErS via Article aNnotations (PARMESAN), an open-source computational tool that automates the extraction of gene-gene and drug-gene relationships from research literature. Tool is available at https://parmesan.nrihub.org/
ASCVD Risk Estimator Plus

The ASCVD Risk Estimator Plus is developed by the American College of Cardiology (ACC) to provide an individualized estimate of a patient’s 10-year risk of developing atherosclerotic cardiovascular disease (ASCVD) and overall lifetime risk histories. It uses the pooled cohort equation to estimate the initial 10-year ASCVD risk of a patient, and provides an individualized,…
UK Biobank

UK Biobank is a globally accessible biomedical database and research resource with genetic and health information supporting research into various serious illnesses.
Novel in-ear sensors to monitor brain activity and lactate levels

University of California, San Diego researchers have developed an in-ear sensor system that combines electrochemical and electrophysiological sensors on a flexible substrate integrated with earphones. This system allows for the simultaneous monitoring of lactate levels and various brain states using electroencephalography (EEG), electrooculography (EOG), and electrodermal activity.During exercise, the device detected increased lactate levels in…
IM3PACT – new computational model to predict response to glucose-responsive insulin designs

MIT researchers have developed a computational model called IM3PACT to predict the human body’s response to different glucose-responsive insulin (GRI) designs. Researchers created this model to analyze a discontinued GRI clinical trial that showed limited effectiveness in humans despite success in animal studies. The IM3PACT model revealed differences in the behavior of a mannose receptor…
Research compares different types of electric fields to speed up chronic wound healing

Researchers at Chalmers University of Technology in Sweden and the University of Freiburg in Germany have created a compact bioelectronic platform to compare different types of electric stimulation to speed up the healing process for chronic wounds. The study looked at the impact of sustained electric fields on wound healing in healthy and diabetic human…
Researchers Identify Role of FHL5 Gene in Vascular Disease

Researchers at the University of Virginia Health Systems have identified a gene called FHL5 that plays a crucial role in determining the risk for serious vascular conditions such as heart attacks, aneurysms, and coronary artery disease. Researchers utilized a multimodal approach through statistical fine-mapping, epigenomic profiling, and ex vivo analysis of human coronary artery tissues.…
DNA Methylation Analysis Enhances Prediction of Type 2 Diabetes Risk

A study by the University of Edinburgh has found that analyzing DNA methylation (changes to DNA in the blood) can improve the prediction of an individual’s risk of developing type 2 diabetes. The research was conducted on almost 15,000 individuals from the Generation Scotland cohort to predict the likelihood of developing type 2 diabetes years…